The reduction of N-hydroxy-4-acetylaminobiphenyl by the intestinal microflora of the rat

The role of the intestinal flora in the conversion of N-hydroxy-4-acetyl-aminobiphenyl (N-OH-AABP) to 4-acetylaminobiphenyl has been examined. This reaction, which reverses the metabolic activation of the parent carcinogen, can be demonstrated in cultures of some bacteria indigenous to the intestina...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1975-11, Vol.35 (11 Pt 1), p.2962
Hauptverfasser:	Wheeler, L A, Soderberg, F B, Goldman, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminobiphenyl Compounds - metabolism Anaerobiosis Animals Brain - microbiology Carcinogens - metabolism Cecum - microbiology Germ-Free Life Hydrolysis Hydroxamic Acids - metabolism Intestines - microbiology Kidney - microbiology Liver - microbiology Neoplasms, Experimental - chemically induced Rats
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!