neurogenin2 Elicits the Genesis of Retinal Neurons from Cultures of Nonneural Cells

neurogenin2 (ngn2) encodes a basic helix-loop-helix transcription factor and plays an important role in neurogenesis from migratory neural crest cells. Its role in retinal development is poorly understood. We observed that in the developing chick retina, ngn2 was expressed in a subpopulation of prol...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2001-12, Vol.98 (26), p.15014-15019
Hauptverfasser:	Yan, Run-Tao, Ma, Wen-Xin, Wang, Shu-Zhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amacrine cells Animals Base Sequence Basic Helix-Loop-Helix Transcription Factors Biological Sciences Cell culture techniques Cell cycle Cell Differentiation - physiology Cells, Cultured Cellular biology Chick Embryo Cultured cells DNA Primers Ganglia Immunohistochemistry In Situ Hybridization Mice Nerve Tissue Proteins - genetics Nerve Tissue Proteins - physiology neurogenin 2 gene neurogenin2 gene Neurons Neurons - cytology Photoreceptor Cells, Vertebrate - cytology Photoreceptors Retina Retina - cytology Retina - embryology Retinal neurons Stem cells
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