Extraordinary Variation in a Diversified Family of Immune-Type Receptor Genes

Immune inhibitory receptor genes that encode a variable (V) region, a unique V-like C2 (V/C2) domain, a transmembrane region, and a cytoplasmic tail containing immunoreceptor tyrosine-based inhibition motifs (ITIMs) have been described previously in two lineages of bony fish. In the present study, e...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2001-11, Vol.98 (24), p.13832-13837
Hauptverfasser:	Hawke, Noel A., Yoder, Jeffrey A., Haire, Robert N., Mueller, M. Gail, Litman, Ronda T., Miracle, Ann L., Stuge, Tor, Shen, Linling, Miller, Norman, Litman, Gary W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals B lymphocytes Base Sequence Biological Sciences Cell lines DNA, Complementary Evolution, Molecular Fish Gene Expression Genes Genetic Variation Genomics Ictaluridae Ictalurus punctatus Immunoglobulin Variable Region - classification Immunoglobulin Variable Region - genetics Immunology immunoreceptor tyrosine-based inhibition motif Learning resources centers Leukocytes Lymphocyte Culture Test, Mixed Molecular Sequence Data Receptors Receptors, Immunologic - classification Receptors, Immunologic - genetics RNA T lymphocytes
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