Expression of Clostridium perfringens enterotoxin receptors claudin-3 and claudin-4 in prostate cancer epithelium

The mRNA for Rvp.1 (rat ventral prostate) increases in abundance before gland involution after androgen deprivation. Rvp.1 is homologous to CPE-R, the high-affinity intestinal epithelial receptor for Clostridium perfringens enterotoxin (CPE), and is sufficient to mediate CPE binding and trigger subs...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2001-11, Vol.61 (21), p.7878-7881
Hauptverfasser:	HAIYAN LONG, CREAN, Colin D, LEE, Wei-Hua, CUMMINGS, O. William, GABIG, Theodore G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - metabolism Adenocarcinoma - secondary Androgens - physiology Animals Biological and medical sciences Bone Marrow Neoplasms - drug therapy Bone Marrow Neoplasms - metabolism Bone Marrow Neoplasms - secondary Cercopithecus aethiops Claudin-3 Claudin-4 Clostridium perfringens - genetics Clostridium perfringens - metabolism Enterotoxins - metabolism Enterotoxins - toxicity Epithelial Cells - metabolism Epithelial Cells - pathology Humans Male Medical sciences Membrane Proteins - biosynthesis Membrane Proteins - genetics Neoplasms, Hormone-Dependent - drug therapy Neoplasms, Hormone-Dependent - metabolism Nephrology. Urinary tract diseases Prostatic Neoplasms - drug therapy Prostatic Neoplasms - metabolism RNA, Messenger - biosynthesis RNA, Messenger - genetics Tumors of the urinary system Urinary tract. Prostate gland Vero Cells
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