KGF AND HGF ARE GROWTH FACTORS FOR MESOTHELIAL CELLS IN PLEURAL LAVAGE FLUID AFTER INTRATRACHEAL ASBESTOS

Mesothelial cells proliferate soon after asbestos deposition in the lung. The present study investigates whether the known mesothelial cell mitogens keratinocyte growth factor (KGF)and hepatocyte growth factor (HGF)are present in the lung and specifically in the pleural cavity during the phase of me...

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Veröffentlicht in:	Experimental lung research 2001, Vol.27 (7), p.605-616
Hauptverfasser:	ADAMSON, I. Y. R, BAKOWSKA, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asbestos, Crocidolite - administration & dosage Asbestos, Crocidolite - toxicity Biological and medical sciences Bronchoalveolar Lavage Fluid Cell Count Cell Division Cells, Cultured Chemical and industrial products toxicology. Toxic occupational diseases Epithelium - drug effects Epithelium - growth & development Epithelium - pathology Fibroblast Growth Factor 7 Fibroblast Growth Factors - metabolism Hepatocyte Growth Factor - metabolism Hepatocyte Growth Factor Keratinocyte Growth Factor Pleural Disease Inorganic dusts (pneumoconiosises) and organic dusts (byssinosis etc.) Intubation, Intratracheal Lung - drug effects Lung - metabolism Lung - pathology Male Medical sciences Pleura - drug effects Pleura - metabolism Pleura - pathology Rats Rats, Sprague-Dawley Toxicology
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