Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes

Phorbol 12-myristate 13-acetate (PMA), interleukin-1 (IL-1) and lipopolysaccharide (LPS) induce similar responses in a variety of cell types, including chondrocytes. These responses include the release of arachidonic acid (AA) and the production of prostaglandin E2 (PGE2). Although PMA is known to s...

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Veröffentlicht in:	Osteoarthritis and cartilage 1994-12, Vol.2 (4), p.269
Hauptverfasser:	Conquer, J A, Jones, S A, Cruz, T F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle Chondrocytes - drug effects Chondrocytes - enzymology Dinoprostone - biosynthesis Down-Regulation Interleukin-1 - pharmacology Lipopolysaccharides - pharmacology Phospholipase D - metabolism Staurosporine - pharmacology Tetradecanoylphorbol Acetate - analogs & derivatives
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