Cardiomyocytes Induce Endothelial Cells to Trans-Differentiate into Cardiac Muscle: Implications for Myocardium Regeneration

The concept of tissue-restricted differentiation of postnatal stem cells has been challenged by recent evidence showing pluripotency for hematopoietic, mesenchymal, and neural stem cells. Furthermore, rare but well documented examples exist of already differentiated cells in developing mammals that...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2001-09, Vol.98 (19), p.10733-10738
Hauptverfasser:	Condorelli, G., Borello, U., De Angelis, L., Latronico, M., Sirabella, D., Coletta, M., Galli, R., Balconi, G., Follenzi, A., Frati, G., M. G. Cusella De Angelis, Gioglio, L., Amuchastegui, S., Adorini, L., Naldini, L., Vescovi, A., Dejana, E., Cossu, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - cytology Biological Sciences Cell Differentiation Cell division Cell lines Cells, Cultured Cellular differentiation Embryonic stem cells Endothelial cells Endothelium, Vascular - cytology Heart Heart - physiology Human umbilical vein endothelial cells Humans Mice Muscular system Myocardial Ischemia Myocardium Myocardium - cytology Neural stem cells Progenitor cells Regeneration - physiology Signal Transduction Stem cells Tissues
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