A rapid procedure for initial drug evaluation

The overall aim of this work is to develop computer simulations to aid in the selection of proposed medicines and identify those most likely to succeed. One important feature is a systems approach to simulate both the target area with which the drug is designed to interact as well as the surrounding...

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Bibliographische Detailangaben
Veröffentlicht in:	Physics in medicine & biology 2001-06, Vol.46 (6), p.N139-N147
Hauptverfasser:	Macpherson, A K, Neti, S, Macpherson, P A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amlodipine - pharmacology Antihypertensive Agents - pharmacology Arterioles - drug effects Biological and medical sciences Calcium Channels - metabolism Clinical trial. Drug monitoring Computer Simulation Computerized, statistical medical data processing and models in biomedicine Dose-Response Relationship, Drug Drug Evaluation - methods General pharmacology Humans Hypertension - drug therapy Ions Medical sciences Models and simulation Models, Theoretical Muscle Contraction - drug effects Pharmacology. Drug treatments Sodium - metabolism Software
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