Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps

Late bleb leaks may follow months to years after filtering surgery especially with the use of antimetabolites. Complications related to beb leaks may lead to a decrease in visual acuity through complicated hypotony or ocular infection. Our retrospective study reports the anatomical and functional re...

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Veröffentlicht in:Journal français d'ophtalmologie 2001-05, Vol.24 (5), p.482
Hauptverfasser: Hamard, P, Tazartes, M, Ayed, T, Quesnot, S, Hamard, H
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container_title Journal français d'ophtalmologie
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creator Hamard, P
Tazartes, M
Ayed, T
Quesnot, S
Hamard, H
description Late bleb leaks may follow months to years after filtering surgery especially with the use of antimetabolites. Complications related to beb leaks may lead to a decrease in visual acuity through complicated hypotony or ocular infection. Our retrospective study reports the anatomical and functional results of bleb reconstruction involving the resection of the bleb associated with the covering of the trabeculectomy site with a rotational conjunctival flap. and methods: Twelve eyes of eleven patients with filtering bleb leaks occurring 3 months to 5 years after successful trabeculectomy (58.3% with adjunct of antimetabolites) underwent bleb surgical reconstruction between november 1995 and June 1999 and were followed until March 2000. Surgical bleb reconstruction was indicated because of persistent or a recurring bleb leak despite conservative medical treatment and blood bleb injections in seven cases. Complications associated with bleb leaks were chronical hypotony (9 cases), athalamy (1 case), hypotony maculopathy (1 case), and endophtalmitis with athalamy (1 case). Three patients had normal IOP but a bleb leak responsible for epiphora. All eyes were treated surgically through bleb excision and conjunctival closure was performed by rotational conjunctival flap. Mean (+/- SD) preoperative IOP was 5.1+/-3.5mmHg (range: 2 to 14mmHg). Mean (+/- SD) postoperative IOP evaluated before any other operation for uncontrolled IOP was 12.7+/-3.1mmHg (range: 6 to 15mmHg). Mean follow-up was 26.7+/-16.9 months (range: 9 to 64 months). All the complications related to the bleb leak resolved after bleb reconstruction. Surgery definively stopped the leak in 10 cases (83.3%) and allowed IOP control without treatment in 50.0% of the cases. Chronic recurring bleb leaks without hypotony occurred in two eyes and required surgery with conjunctival graft which led to a refractory increase in IOP responsible for loss of vision in one case. Bleb resection associated with the covering of the trabeculectomy site with a rotational conjunctival flap is a safe and effective procedure for the treatment of a late bleb leak and its complications. In most of the cases (83.3%), long-term IOP control can be expected without, medical treatment in 50% of the cases. Patients must be aware of the possibility of a recurring Seidel; however, the incidence of this complication remains low.
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Complications related to beb leaks may lead to a decrease in visual acuity through complicated hypotony or ocular infection. Our retrospective study reports the anatomical and functional results of bleb reconstruction involving the resection of the bleb associated with the covering of the trabeculectomy site with a rotational conjunctival flap. and methods: Twelve eyes of eleven patients with filtering bleb leaks occurring 3 months to 5 years after successful trabeculectomy (58.3% with adjunct of antimetabolites) underwent bleb surgical reconstruction between november 1995 and June 1999 and were followed until March 2000. Surgical bleb reconstruction was indicated because of persistent or a recurring bleb leak despite conservative medical treatment and blood bleb injections in seven cases. Complications associated with bleb leaks were chronical hypotony (9 cases), athalamy (1 case), hypotony maculopathy (1 case), and endophtalmitis with athalamy (1 case). Three patients had normal IOP but a bleb leak responsible for epiphora. All eyes were treated surgically through bleb excision and conjunctival closure was performed by rotational conjunctival flap. Mean (+/- SD) preoperative IOP was 5.1+/-3.5mmHg (range: 2 to 14mmHg). Mean (+/- SD) postoperative IOP evaluated before any other operation for uncontrolled IOP was 12.7+/-3.1mmHg (range: 6 to 15mmHg). Mean follow-up was 26.7+/-16.9 months (range: 9 to 64 months). All the complications related to the bleb leak resolved after bleb reconstruction. Surgery definively stopped the leak in 10 cases (83.3%) and allowed IOP control without treatment in 50.0% of the cases. Chronic recurring bleb leaks without hypotony occurred in two eyes and required surgery with conjunctival graft which led to a refractory increase in IOP responsible for loss of vision in one case. Bleb resection associated with the covering of the trabeculectomy site with a rotational conjunctival flap is a safe and effective procedure for the treatment of a late bleb leak and its complications. In most of the cases (83.3%), long-term IOP control can be expected without, medical treatment in 50% of the cases. 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Complications related to beb leaks may lead to a decrease in visual acuity through complicated hypotony or ocular infection. Our retrospective study reports the anatomical and functional results of bleb reconstruction involving the resection of the bleb associated with the covering of the trabeculectomy site with a rotational conjunctival flap. and methods: Twelve eyes of eleven patients with filtering bleb leaks occurring 3 months to 5 years after successful trabeculectomy (58.3% with adjunct of antimetabolites) underwent bleb surgical reconstruction between november 1995 and June 1999 and were followed until March 2000. Surgical bleb reconstruction was indicated because of persistent or a recurring bleb leak despite conservative medical treatment and blood bleb injections in seven cases. Complications associated with bleb leaks were chronical hypotony (9 cases), athalamy (1 case), hypotony maculopathy (1 case), and endophtalmitis with athalamy (1 case). Three patients had normal IOP but a bleb leak responsible for epiphora. All eyes were treated surgically through bleb excision and conjunctival closure was performed by rotational conjunctival flap. Mean (+/- SD) preoperative IOP was 5.1+/-3.5mmHg (range: 2 to 14mmHg). Mean (+/- SD) postoperative IOP evaluated before any other operation for uncontrolled IOP was 12.7+/-3.1mmHg (range: 6 to 15mmHg). Mean follow-up was 26.7+/-16.9 months (range: 9 to 64 months). All the complications related to the bleb leak resolved after bleb reconstruction. Surgery definively stopped the leak in 10 cases (83.3%) and allowed IOP control without treatment in 50.0% of the cases. Chronic recurring bleb leaks without hypotony occurred in two eyes and required surgery with conjunctival graft which led to a refractory increase in IOP responsible for loss of vision in one case. Bleb resection associated with the covering of the trabeculectomy site with a rotational conjunctival flap is a safe and effective procedure for the treatment of a late bleb leak and its complications. In most of the cases (83.3%), long-term IOP control can be expected without, medical treatment in 50% of the cases. Patients must be aware of the possibility of a recurring Seidel; however, the incidence of this complication remains low.</description><subject>Adult</subject><subject>Aged</subject><subject>Antimetabolites - therapeutic use</subject><subject>Blister - etiology</subject><subject>Blister - surgery</subject><subject>Combined Modality Therapy</subject><subject>Conjunctival Diseases - etiology</subject><subject>Conjunctival Diseases - surgery</subject><subject>Female</subject><subject>Fluorouracil - therapeutic use</subject><subject>Glaucoma, Angle-Closure - surgery</subject><subject>Glaucoma, Open-Angle - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mitomycin - therapeutic use</subject><subject>Nucleic Acid Synthesis Inhibitors - therapeutic use</subject><subject>Patient Selection</subject><subject>Prognosis</subject><subject>Proportional Hazards Models</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Surgical Flaps</subject><subject>Survival Analysis</subject><subject>Time Factors</subject><subject>Trabeculectomy - adverse effects</subject><subject>Treatment Outcome</subject><issn>0181-5512</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j0tqwzAYhLVoSdK0Vyi6gEGyLNlaltAXBNpF9kaPX4lS2TKS3NLb16HtbGY-BgbmCm0I7WjFOa3X6CbnMyGEtZyv0JpSJlvZNRvUv6d4HGMu3uA4FxMHwNHhAOrDj0fsfCiQLkkH0BknMHHMJc2m-DjiL19OOMWiLqQCXsrzPC7d5wIuqCnfomunQoa7P9-iw9PjYfdS7d-eX3cP-2riTVM5Krggtelaxk1NBQPLnZNaO0YUEVbYTtt2EVArpRWEE8q1BSFrAOcM26L739lp1gPYfkp-UOm7_z_KfgDCh1FS</recordid><startdate>200105</startdate><enddate>200105</enddate><creator>Hamard, P</creator><creator>Tazartes, M</creator><creator>Ayed, T</creator><creator>Quesnot, S</creator><creator>Hamard, H</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200105</creationdate><title>Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps</title><author>Hamard, P ; Tazartes, M ; Ayed, T ; Quesnot, S ; Hamard, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p544-f165602c8735c2163ed5ff9bbf30a06d6d8bd7777e1d99d605015bde692eeffc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Antimetabolites - therapeutic use</topic><topic>Blister - etiology</topic><topic>Blister - surgery</topic><topic>Combined Modality Therapy</topic><topic>Conjunctival Diseases - etiology</topic><topic>Conjunctival Diseases - surgery</topic><topic>Female</topic><topic>Fluorouracil - therapeutic use</topic><topic>Glaucoma, Angle-Closure - surgery</topic><topic>Glaucoma, Open-Angle - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mitomycin - therapeutic use</topic><topic>Nucleic Acid Synthesis Inhibitors - therapeutic use</topic><topic>Patient Selection</topic><topic>Prognosis</topic><topic>Proportional Hazards Models</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Surgical Flaps</topic><topic>Survival Analysis</topic><topic>Time Factors</topic><topic>Trabeculectomy - adverse effects</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hamard, P</creatorcontrib><creatorcontrib>Tazartes, M</creatorcontrib><creatorcontrib>Ayed, T</creatorcontrib><creatorcontrib>Quesnot, S</creatorcontrib><creatorcontrib>Hamard, H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Journal français d'ophtalmologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hamard, P</au><au>Tazartes, M</au><au>Ayed, T</au><au>Quesnot, S</au><au>Hamard, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps</atitle><jtitle>Journal français d'ophtalmologie</jtitle><addtitle>J Fr Ophtalmol</addtitle><date>2001-05</date><risdate>2001</risdate><volume>24</volume><issue>5</issue><spage>482</spage><pages>482-</pages><issn>0181-5512</issn><abstract>Late bleb leaks may follow months to years after filtering surgery especially with the use of antimetabolites. Complications related to beb leaks may lead to a decrease in visual acuity through complicated hypotony or ocular infection. Our retrospective study reports the anatomical and functional results of bleb reconstruction involving the resection of the bleb associated with the covering of the trabeculectomy site with a rotational conjunctival flap. and methods: Twelve eyes of eleven patients with filtering bleb leaks occurring 3 months to 5 years after successful trabeculectomy (58.3% with adjunct of antimetabolites) underwent bleb surgical reconstruction between november 1995 and June 1999 and were followed until March 2000. Surgical bleb reconstruction was indicated because of persistent or a recurring bleb leak despite conservative medical treatment and blood bleb injections in seven cases. Complications associated with bleb leaks were chronical hypotony (9 cases), athalamy (1 case), hypotony maculopathy (1 case), and endophtalmitis with athalamy (1 case). Three patients had normal IOP but a bleb leak responsible for epiphora. All eyes were treated surgically through bleb excision and conjunctival closure was performed by rotational conjunctival flap. Mean (+/- SD) preoperative IOP was 5.1+/-3.5mmHg (range: 2 to 14mmHg). Mean (+/- SD) postoperative IOP evaluated before any other operation for uncontrolled IOP was 12.7+/-3.1mmHg (range: 6 to 15mmHg). Mean follow-up was 26.7+/-16.9 months (range: 9 to 64 months). All the complications related to the bleb leak resolved after bleb reconstruction. Surgery definively stopped the leak in 10 cases (83.3%) and allowed IOP control without treatment in 50.0% of the cases. Chronic recurring bleb leaks without hypotony occurred in two eyes and required surgery with conjunctival graft which led to a refractory increase in IOP responsible for loss of vision in one case. Bleb resection associated with the covering of the trabeculectomy site with a rotational conjunctival flap is a safe and effective procedure for the treatment of a late bleb leak and its complications. In most of the cases (83.3%), long-term IOP control can be expected without, medical treatment in 50% of the cases. Patients must be aware of the possibility of a recurring Seidel; however, the incidence of this complication remains low.</abstract><cop>France</cop><pmid>11397984</pmid></addata></record>
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source MEDLINE; Alma/SFX Local Collection
subjects Adult
Aged
Antimetabolites - therapeutic use
Blister - etiology
Blister - surgery
Combined Modality Therapy
Conjunctival Diseases - etiology
Conjunctival Diseases - surgery
Female
Fluorouracil - therapeutic use
Glaucoma, Angle-Closure - surgery
Glaucoma, Open-Angle - surgery
Humans
Male
Middle Aged
Mitomycin - therapeutic use
Nucleic Acid Synthesis Inhibitors - therapeutic use
Patient Selection
Prognosis
Proportional Hazards Models
Retrospective Studies
Risk Factors
Surgical Flaps
Survival Analysis
Time Factors
Trabeculectomy - adverse effects
Treatment Outcome
title Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps
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