The Disintegrin Kistrin Inhibits Neurite Extension from Spiral Ganglion Explants Cultured on Laminin

The influence of laminin-1 (LN) and tenascin-C (TN), extracellular matrix molecules expressed spatially and temporally along the neural growth route from spiral ganglion (SG) neurons to the cochlear sensory cells, was evaluated in cultured SG explants from postnatal day 4 rats. Increasing concentrat...

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Veröffentlicht in:	Audiology & neurotology 2001-03, Vol.6 (2), p.57-65
Hauptverfasser:	Aletsee, Christoph, Mullen, Lina, Kim, David, Pak, Kwang, Brors, Dominik, Dazert, Stefan, Ryan, Allen F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell differentiation, maturation, development, hematopoiesis Cell physiology Culture Techniques Disintegrins - administration & dosage Disintegrins - pharmacology Dose-Response Relationship, Drug Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation Fundamental and applied biological sciences. Psychology Immunohistochemistry Laminin - metabolism Molecular and cellular biology Neurites - drug effects Neurites - metabolism Original Paper Peptides - administration & dosage Peptides - pharmacology Rats Rats, Sprague-Dawley Spiral Ganglion - metabolism Tenascin - metabolism Vertebrates: nervous system and sense organs
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