Mitomycin C Influence on Inhibition of Cellular Proliferation and Subsequent Synthesis of Type I Collagen and Laminin in Primary and Recurrent Pterygia

The purpose was to investigate the biological effects of mitomycin C (MMC) on the inhibition of cellular proliferation and the subsequent synthesis of extracellular matrix like type I collagen (PIP) and laminin on primary and recurrent pterygia. The 3 H-thymidine assay for cellular proliferation was...

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Veröffentlicht in:	Ophthalmic research 2001-05, Vol.33 (3), p.140-146
Hauptverfasser:	Lee, Jong Soo, Oum, Boo Sup, Lee, Sang Hyup
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cell Division - drug effects Collagen - biosynthesis Dose-Response Relationship, Drug Enzyme-Linked Immunosorbent Assay Extracellular Matrix - metabolism Fibroblasts - metabolism Humans Laminin - biosynthesis Male Mitomycin - pharmacology Original Paper Pterygium - metabolism Recurrence Time Factors
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