Cytotoxicity of Carcinogenic Aromatic Amides in Normal and Xeroderma Pigmentosum Fibroblasts With Different DNA Repair Capabilities

The effect of exposure to UV irradiation or to the N-acetoxy-ester derivatives of four carcinogenic aromatic amides, 4-acetylaminobiphenyl (AABP), 2-acetylaminofluorene (AAF), 2-acetylaminophenanthrene, and 4-acetylaminostilbene, on cell survival was compared in strains of cultured human fibroblasts...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1975-06, Vol.54 (6), p.1287-1294
Hauptverfasser:	Maher, Veronica M., Birch, Nancy, Otto, James R., McCormick, J. Justin
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acetylaminofluorene - analogs & derivatives 2-Acetylaminofluorene - toxicity Amides - toxicity Biphenyl Compounds - toxicity Carcinogens - toxicity Cell Survival - drug effects Cell Survival - radiation effects Cells, Cultured DNA Repair Esters Fibroblasts - drug effects Fibroblasts - metabolism Fibroblasts - radiation effects Humans Phenanthrenes - toxicity Radiation Effects Stilbenes - toxicity Sulfates Ultraviolet Rays Xeroderma Pigmentosum - metabolism
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