Proteinase Inhibitors I and II from Potatoes Block UVB-Induced AP-1 Activity by Regulating the AP-1 Protein Compositional Patterns in JB6 Cells

Proteinase inhibitor I (Inh I) and proteinase inhibitor II (Inh II) from potato tubers are effective proteinase inhibitors of chymotrypsin and trypsin. Inh I and Inh II were shown to suppress irradiation-induced transformation in mouse embryo fibroblasts suggesting that they possess anticarcinogenic...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2001-05, Vol.98 (10), p.5786-5791
Hauptverfasser:	Liu, Guangming, Chen, Nanyue, Kaji, Akira, Bode, Ann M., Ryan, Clarence A., Dong, Zigang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Base Sequence Biological Sciences Blood Proteins - isolation & purification Blood Proteins - pharmacology Cell culture techniques Cell Line Cell lines Cells Cultured cells DNA DNA Primers Epidermal cells Gene expression regulation Medical research NF-kappa B - metabolism Nuclear proteins Potatoes Protease inhibitors Solanum tuberosum - metabolism Transactivation Transcription Factor AP-1 - antagonists & inhibitors Transcription Factor AP-1 - metabolism Transcription Factor AP-1 - radiation effects Ultraviolet radiation Ultraviolet Rays
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