Carcinogenicity of estrogens in human breast epithelial cells

Epidemiological and clinical evidences indicate that breast cancer risk is associated with prolonged ovarian function that results in elevated circulating levels of steroid hormones. Principal among these is estrogen, which is associated with two important risk factors, early onset of menarche and l...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2001-01, Vol.109 (1), p.39-52
Hauptverfasser:	RUSSO, JOSE, HU, YUN FU, TAHIN, QUIVO, MIHAILA, DANA, SLATER, CAROLYN, LAREEF, M. HASAN, RUSSO, IRMA H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast - cytology Breast - drug effects Breast - metabolism breast cancer Breast Neoplasms - etiology Breast Neoplasms - genetics carcinogenesis Carcinogens - toxicity Cell Line, Transformed Colony-Forming Units Assay Diethylstilbestrol - toxicity epithelial cells Epithelial Cells - cytology Epithelial Cells - drug effects Epithelial Cells - metabolism Estradiol - toxicity estrogens Estrogens - toxicity Female Gynecology. Andrology. Obstetrics Humans Loss of Heterozygosity Mammary gland diseases Medical sciences Phenotype Receptors, Estrogen - metabolism Transformation, Genetic - drug effects Tumors
Online-Zugang:	Volltext
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