Disruption of the Cockayne Syndrome B Gene Impairs Spontaneous Tumorigenesis in Cancer-Predisposed Ink4a/ARF Knockout Mice
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| Veröffentlicht in: | Molecular and Cellular Biology 2001-03, Vol.21 (5), p.1810-1818 |
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| container_title | Molecular and Cellular Biology |
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| creator | Lu, Yi Lian, Hanzhou Sharma, Prerna Schreiber-Agus, Nicole Russell, Robert G. Chin, Lynda van der Horst, Gijsbertus T. J. Bregman, David B. |
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| doi_str_mv | 10.1128/MCB.21.5.1810-1818.2001 |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/MCB.21.5.1810-1818.2001</identifier><identifier>PMID: 11238917</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Age Factors ; Animals ; Apoptosis ; ARF gene ; ARF protein ; Cell Division ; Cockayne Syndrome - genetics ; Crosses, Genetic ; CSB gene ; Cyclin-Dependent Kinase Inhibitor p16 - genetics ; DNA Dynamics and Chromosome Structure ; DNA Helicases - genetics ; DNA Helicases - physiology ; DNA Repair ; DNA Repair Enzymes ; Fibroblasts - metabolism ; Fibrosarcoma - metabolism ; Flow Cytometry ; Genes, p53 - genetics ; Genetic Predisposition to Disease ; genotoxin ; Genotype ; Immunoblotting ; In Situ Nick-End Labeling ; Ink4a gene ; Ink4a protein ; Lymphoma - metabolism ; Mice ; Mice, Knockout ; Neoplasms - genetics ; Poly-ADP-Ribose Binding Proteins ; Proteins - genetics ; ras Proteins - metabolism ; RNA, Messenger - metabolism ; Time Factors ; Transformation, Genetic ; Tumor Suppressor Protein p14ARF ; Tumor Suppressor Protein p53 - metabolism ; Ultraviolet Rays</subject><ispartof>Molecular and Cellular Biology, 2001-03, Vol.21 (5), p.1810-1818</ispartof><rights>Copyright © 2001 American Society for Microbiology 2001</rights><rights>Copyright © 2001, American Society for Microbiology 2001</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c527t-73caf3e879f30e55a5dafc6d87e174f834f1ebc5dc34e23cd7f0a28b0fefa2393</citedby><cites>FETCH-LOGICAL-c527t-73caf3e879f30e55a5dafc6d87e174f834f1ebc5dc34e23cd7f0a28b0fefa2393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC86742/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC86742/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11238917$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lu, Yi</creatorcontrib><creatorcontrib>Lian, Hanzhou</creatorcontrib><creatorcontrib>Sharma, Prerna</creatorcontrib><creatorcontrib>Schreiber-Agus, Nicole</creatorcontrib><creatorcontrib>Russell, Robert G.</creatorcontrib><creatorcontrib>Chin, Lynda</creatorcontrib><creatorcontrib>van der Horst, Gijsbertus T. J.</creatorcontrib><creatorcontrib>Bregman, David B.</creatorcontrib><title>Disruption of the Cockayne Syndrome B Gene Impairs Spontaneous Tumorigenesis in Cancer-Predisposed Ink4a/ARF Knockout Mice</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Article Usage Stats
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</description><subject>Age Factors</subject><subject>Animals</subject><subject>Apoptosis</subject><subject>ARF gene</subject><subject>ARF protein</subject><subject>Cell Division</subject><subject>Cockayne Syndrome - genetics</subject><subject>Crosses, Genetic</subject><subject>CSB gene</subject><subject>Cyclin-Dependent Kinase Inhibitor p16 - genetics</subject><subject>DNA Dynamics and Chromosome Structure</subject><subject>DNA Helicases - genetics</subject><subject>DNA Helicases - physiology</subject><subject>DNA Repair</subject><subject>DNA Repair Enzymes</subject><subject>Fibroblasts - metabolism</subject><subject>Fibrosarcoma - metabolism</subject><subject>Flow Cytometry</subject><subject>Genes, p53 - genetics</subject><subject>Genetic Predisposition to Disease</subject><subject>genotoxin</subject><subject>Genotype</subject><subject>Immunoblotting</subject><subject>In Situ Nick-End Labeling</subject><subject>Ink4a gene</subject><subject>Ink4a protein</subject><subject>Lymphoma - metabolism</subject><subject>Mice</subject><subject>Mice, Knockout</subject><subject>Neoplasms - genetics</subject><subject>Poly-ADP-Ribose Binding Proteins</subject><subject>Proteins - genetics</subject><subject>ras Proteins - metabolism</subject><subject>RNA, Messenger - metabolism</subject><subject>Time Factors</subject><subject>Transformation, Genetic</subject><subject>Tumor Suppressor Protein p14ARF</subject><subject>Tumor Suppressor Protein p53 - metabolism</subject><subject>Ultraviolet Rays</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUUtv1DAQjhCILoW_AObCLakfydqRuHQDLStagWg5W15nvGua2KmdUC2_Hke7onDiMqPRfI_RfFn2huCCECrOrptVQUlRFUQQnKciCooxeZItCK5FXlVl_TRbYMpxzhlenmQvYvyBMV7WmD3PTpIGEzXhi-zXBxvDNIzWO-QNGneAGq_v1N4Butm7Nvge0ApdQprX_aBsiOhm8G5UDvwU0e3U-2C3aR1tRNahRjkNIf8aoLVx8BFatHZ3pTo7_3aBPruk7acRXVsNL7NnRnURXh37afb94uNt8ym_-nK5bs6vcl1RPqb7tTIMBK8Nw1BVqmqV0ctWcCC8NIKVhsBGV61mJVCmW26womKDDRhFWc1Os_cH3WHa9NBqcGNQnRyC7VXYS6-s_Hfj7E5u_U8plrykif7uSA_-foI4yt5GDV13-IAknFeC0NmHH4A6-BgDmD8WBMs5NZlSk5TISs6pzUXIObXEfP33hY-8Y0wJsDoArDM-9OrBh66Vo9p3PpiQPm6jZP93eXsQ2dnt7sEGkCr2stebRzT7DeiWt2M</recordid><startdate>20010301</startdate><enddate>20010301</enddate><creator>Lu, Yi</creator><creator>Lian, Hanzhou</creator><creator>Sharma, Prerna</creator><creator>Schreiber-Agus, Nicole</creator><creator>Russell, Robert G.</creator><creator>Chin, Lynda</creator><creator>van der Horst, Gijsbertus T. 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>11238917</pmid><doi>10.1128/MCB.21.5.1810-1818.2001</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0270-7306 |
| ispartof | Molecular and Cellular Biology, 2001-03, Vol.21 (5), p.1810-1818 |
| issn | 0270-7306 1098-5549 1098-5549 |
| language | eng |
| recordid | cdi_pubmed_primary_11238917 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Age Factors Animals Apoptosis ARF gene ARF protein Cell Division Cockayne Syndrome - genetics Crosses, Genetic CSB gene Cyclin-Dependent Kinase Inhibitor p16 - genetics DNA Dynamics and Chromosome Structure DNA Helicases - genetics DNA Helicases - physiology DNA Repair DNA Repair Enzymes Fibroblasts - metabolism Fibrosarcoma - metabolism Flow Cytometry Genes, p53 - genetics Genetic Predisposition to Disease genotoxin Genotype Immunoblotting In Situ Nick-End Labeling Ink4a gene Ink4a protein Lymphoma - metabolism Mice Mice, Knockout Neoplasms - genetics Poly-ADP-Ribose Binding Proteins Proteins - genetics ras Proteins - metabolism RNA, Messenger - metabolism Time Factors Transformation, Genetic Tumor Suppressor Protein p14ARF Tumor Suppressor Protein p53 - metabolism Ultraviolet Rays |
| title | Disruption of the Cockayne Syndrome B Gene Impairs Spontaneous Tumorigenesis in Cancer-Predisposed Ink4a/ARF Knockout Mice |
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