Glutamine protects mitochondrial structure and function in oxygen toxicity

Departments of 2 Medicine and 1 Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206 Glutamine is an important mitochondrial substrate implicated in the protection of cells from oxidant injury, but the mechanisms of its action are incompletely understood. Human pulmonary...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2001-04, Vol.280 (4), p.779-L791
Hauptverfasser:	Ahmad, Shama, White, Carl W, Chang, Ling-Yi, Schneider, Barbara K, Allen, Corrie B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Cell Division - drug effects Cell Survival - drug effects Epithelial Cells - metabolism Glutamine - deficiency Glutamine - pharmacology Humans Hyperoxia - pathology Hyperoxia - physiopathology Intracellular Membranes - physiology Lung - metabolism Lung - pathology Membrane Potentials - drug effects Mitochondria - drug effects Mitochondria - physiology Mitochondria - ultrastructure Oxygen - poisoning Oxygen Consumption - drug effects Tumor Cells, Cultured - metabolism
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