An Acth-Activated Protein Tyrosine Phosphatase (PTP) is Modulated by Pka-Mediated Phosphorylation

In adrenal cortex, ACTH regulation of steroidogenesis depends on PKA-dependent serine/threonine phosphorylation and also on the activity of protein tyrosine phosphatases (PTPs). In addition, ACTH increases total PTPs involving at least three soluble PTPs (50, 82 and 115 kDa). Serine/threonine phosph...

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Veröffentlicht in:	Endocrine research 2000-01, Vol.26 (4), p.609-614
Hauptverfasser:	Paz, Cristina, Maciel, Fabiana Cornejo, Poderoso, Cecilia, Gorostizaga, Alejandra, Podestá, Ernesto J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - pharmacology Adrenocorticotropic Hormone - pharmacology Animals Cyclic AMP-Dependent Protein Kinases - metabolism Enzyme Activation Male Phosphorylation Protein Tyrosine Phosphatases - metabolism Rats Rats, Wistar Zona Fasciculata - enzymology
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