The Crystal Structure of the Nitrogen Regulation Fragment of the Yeast Prion Protein Ure2p

The yeast nonchromosomal gene [URE3] is due to a prion form of the nitrogen regulatory protein Ure2p. It is a negative regulator of nitrogen catabolism and acts by inhibiting the transcription factor Gln3p. Ure2p residues 1-80 are necessary for prion generation and propagation. The C-terminal fragme...

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Veröffentlicht in:	Proc Natl Acad Sci USA 2001-02, Vol.98 (4), p.1459-1464
Hauptverfasser:	Umland, Timothy C., Taylor, Kimberly L., Rhee, Sangkee, Wickner, Reed B., Davies, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Atoms Biochemistry Biological Sciences CRYSTAL STRUCTURE Crystallography, X-Ray Crystals Dimers Fungal Proteins - chemistry Fungal Proteins - genetics Glutathione Peroxidase Glutathione Transferase - chemistry Goods and services tax MATERIALS SCIENCE Models, Molecular Molecular Sequence Data Monomers Mutation NATIONAL SYNCHROTRON LIGHT SOURCE NITROGEN Nitrogen - metabolism NSLS Prions Protein Structure, Secondary PROTEINS Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics REGULATIONS Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Solvents Ure2 protein URE3 gene Yeast YEASTS
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