TNF-alpha increases entry of macromolecules into luminal endothelial cell glycocalyx

Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia 22906 The endothelial luminal glycocalyx has been largely ignored as a target in vascular pathophysiology even though it occupies a key location. As a model of the inflammatory response, we t...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2000-12, Vol.279 (6), p.H2815-H2823
Hauptverfasser:	Henry, Charmaine B. S, Duling, Brian R
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Albumins - pharmacokinetics Animals Anticoagulants - pharmacology Blood Proteins - metabolism Cell Adhesion - drug effects Cell Adhesion - immunology Cricetinae Dextrans - pharmacokinetics Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Erythrocytes - physiology Fluorescein-5-isothiocyanate - analogs & derivatives Fluorescein-5-isothiocyanate - pharmacokinetics Glycocalyx - drug effects Glycocalyx - metabolism Immunoglobulin G - pharmacology Leukocytes - cytology Leukocytes - physiology Macromolecular Substances Male Mesocricetus Microcirculation - physiology Polysaccharides - pharmacology Scrotum Tumor Necrosis Factor-alpha - pharmacology
Online-Zugang:	Volltext
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