Reactions of peroxynitrite in the mitochondrial matrix

Superoxide radical (O 2 −) and nitric oxide (NO) produced at the mitochondrial inner membrane react to form peroxynitrite (ONOO −) in the mitochondrial matrix. Intramitochondrial ONOO − effectively reacts with a few biomolecules according to reaction constants and intramitochondrial concentrations....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Free radical biology & medicine 2000-08, Vol.29 (3), p.349-356
Hauptverfasser:	Valdez, Laura B., Alvarez, Silvia, Arnaiz, Silvia Lores, Schöpfer, Francisco, Carreras, Marı́a C., Poderoso, Juan José, Boveris, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascorbic Acid - metabolism Blotting, Western Carbon Dioxide - metabolism Free radicals Glutathione - metabolism GSH oxidation Inhibitory Concentration 50 Kinetics Mice Mitochondria Mitochondria, Liver - metabolism Mitochondrial protein nitration NAD - metabolism NADH-oxidation Nitrates - metabolism Oxidation-Reduction Peroxynitrite Spectrometry, Fluorescence Superoxide production Superoxides - metabolism Tyrosine - metabolism Ubiquinol oxidation Ubiquinone - analogs & derivatives Ubiquinone - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!