Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase

The cell-free activation of human neutrophil NADPH oxidase is enhanced by actin, and actin filaments formed during activation are suggested to stabilize the oxidase. In an attempt to elucidate the mechanism, we examined the protein-protein interactions between actin and cytosolic components of the o...

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Veröffentlicht in:	Biochemical and biophysical research communications 2000-10, Vol.276 (3), p.1186
Hauptverfasser:	Tamura, M, Kai, T, Tsunawaki, S, Lambeth, J D, Kameda, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Binding Sites Humans NADPH Oxidases - chemistry NADPH Oxidases - genetics NADPH Oxidases - metabolism Neutrophils - enzymology Neutrophils - metabolism Phosphoproteins - genetics Phosphoproteins - metabolism Protein Binding rac GTP-Binding Proteins - metabolism rac1 GTP-Binding Protein - metabolism RAC2 GTP-Binding Protein Recombinant Proteins - metabolism Sequence Deletion - genetics Surface Plasmon Resonance Thermodynamics
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