SIMULTANEOUS TESTING STRATEGY FOR COMPARING TWO TREATMENTS IN A STRATIFIED BINOMIAL TRIAL

The Mantel-Haenszel (M-H) procedure is commonly used to compare two treatments in a stratified binomial trial. However, this procedure is asymptotically optimal only if the odds ratio is constant across strata. We propose an alternative analytic strategy based on the simultaneous use of two statisti...

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Veröffentlicht in:	Journal of biopharmaceutical statistics 2000-09, Vol.10 (3), p.335-349
Hauptverfasser:	Railkar, R. A., Mehrotra, D. V., Iglewicz, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - therapeutic use Aged Binomial Distribution Data Interpretation, Statistical Humans Mantel-Haenszel procedure Metoprolol - therapeutic use Middle Aged Myocardial Infarction - drug therapy Myocardial Infarction - mortality Odds Ratio Proportions Randomized Controlled Trials as Topic - statistics & numerical data Sample Size Treatment Outcome Weighted averaging
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