Analgesic abuse syndrome: A frequently overlooked cause of reversible renal failure

The incidence of analgesic nephropathy in the United States is greater than previously reported. Because of the characteristic radiographic features of papillary necrosis, this diagnosis may be made while it is still clinically unsuspected. Early diagnosis is extremely important because cessation of...

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Veröffentlicht in:Urology 1975-06, Vol.5 (6), p.728-732
Hauptverfasser: Goldberger, Lawrence E., Talner, Lee B.
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Talner, Lee B.
description The incidence of analgesic nephropathy in the United States is greater than previously reported. Because of the characteristic radiographic features of papillary necrosis, this diagnosis may be made while it is still clinically unsuspected. Early diagnosis is extremely important because cessation of analgesic abuse may avert progressive renal damage. Uncovering the diagnosis calls for special care in obtaining the telltale history. This must be sought in patients with radiographic evidence of papillary necrosis when a history of diabetes mellitus, obstructive uropathy, or sickle cell anemia is absent, or in patients with unexplained nephrocalcinosis or nephrolithiasis.
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subjects Adult
Aged
Anti-Inflammatory Agents, Non-Steroidal
Aspirin - adverse effects
Caffeine - adverse effects
Diagnosis, Differential
Drug Combinations
Female
Humans
Kidney Diseases - chemically induced
Kidney Diseases - epidemiology
Kidney Failure, Chronic - chemically induced
Kidney Papillary Necrosis - chemically induced
Kidney Papillary Necrosis - diagnosis
Kidney Papillary Necrosis - diagnostic imaging
Male
Middle Aged
Phenacetin - adverse effects
Radiography
Substance-Related Disorders
title Analgesic abuse syndrome: A frequently overlooked cause of reversible renal failure
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