Autoimmune thrombocytopenia: A complication of fludarabine therapy in lymphoproliferative disorders

Summary We describe two cases of autoimmune thrombocytopenia precipitated by fludarabine therapy in patients with chronic lymphatic leukaemia. Both were treated with high dose steroids and initially responded with recovery of normal platelet counts. One patient developed recurrent autoimmune thrombo...

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Veröffentlicht in:	Clinical and laboratory haematology 2000-06, Vol.22 (3), p.175-178
Hauptverfasser:	Leach, M., Parsons, R.M., Reilly, J.T., Winfield, D.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anemia, Hemolytic - chemically induced Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Autoimmune thrombocytopenia Biological and medical sciences Drug toxicity and drugs side effects treatment fludarbine Humans Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Leukemia, Lymphocytic, Chronic, B-Cell - complications Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy lymphoproliferative disorders Lymphoproliferative Disorders - complications Lymphoproliferative Disorders - drug therapy Male Medical sciences Pharmacology. Drug treatments Purpura, Thrombocytopenic, Idiopathic - chemically induced Toxicity: blood Vidarabine - adverse effects Vidarabine - analogs & derivatives Vidarabine - therapeutic use
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