Diazeniumdiolates:: Pro- and antioxidant applications of the “NONOates”

Diazeniumdiolates are compounds containing the X-[N(O)NO] − structural unit that as a class offer many advantages as tools for probing the roles of nitric oxide (NO) in biological redox processes. Available examples in which X is a secondary amine group spontaneously generate up to two molecules of...

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Veröffentlicht in:	Free radical biology & medicine 2000-05, Vol.28 (10), p.1463-1469
Hauptverfasser:	Fitzhugh, Anthony L., Keefer, Larry K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - chemistry Antioxidants - pharmacology Cell Death - drug effects Cytochrome P-450 Enzyme Inhibitors Diazeniumdiolates Free radicals Humans In Vitro Techniques Lipoproteins, LDL - metabolism Nitric oxide Nitric Oxide - chemistry Nitric Oxide - pharmacology Nitric Oxide Donors - chemistry Nitric Oxide Donors - pharmacology Nitroso Compounds - chemistry Nitroso Compounds - pharmacology NONOates Oxidants - chemistry Oxidants - pharmacology Oxidation-Reduction Reactive Oxygen Species - metabolism
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