Toxicity of various amyloid β peptide species in cultured human blood-brain barrier endothelial cells: Increased toxicity of Dutch-type mutant

The amyloid β peptide (Aβ) is the major component of the neuritic and cerebrovascular amyloid plaques that are one of the characteristic features of Alzheimer's disease (AD). This peptide has been shown to be toxic to several relevant cell types, including neurons, cerebrovascular smooth muscle...

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