EFFECT OF ARACHIDONIC ACID METABOLIC INHIBITORS ON HYPOXIA REOXYGENATION-INDUCED RENAL CELL INJURY

The present study was undertaken to examine the role of arachidonic acid (AA) metabolites in hypoxia reoxygenation (H R)-induced renal cell injury in rabbit renal cortical slices using AA metabolic inhibitors. Inhibitors of cyclooxygenase (indomethacin and diclofenac sodium) and lipoxygenase pathway...

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Veröffentlicht in:	Renal failure 2000-01, Vol.22 (2), p.143-157
Hauptverfasser:	Kim, Yong Keun, Hwang, Moon Young, Woo, Jae Suk, Jung, Jin Sup, Lee, Sang Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Arachidonic Acid - metabolism Biological and medical sciences Cyclooxygenase Inhibitors - pharmacology Cytochrome P-450 Enzyme Inhibitors Dinoprostone - pharmacology Dose-Response Relationship, Drug Hypoxia - metabolism Hypoxia - pathology Hypoxia - prevention & control Iron Chelating Agents - pharmacology Kidney Cortex - drug effects Kidney Cortex - metabolism Kidney Cortex - pathology Kidney Diseases - metabolism Kidney Diseases - pathology Kidney Diseases - prevention & control L-Lactate Dehydrogenase - metabolism Lipoxygenase Inhibitors - pharmacology Male Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Rabbits Renovascular diseases Reperfusion Injury - metabolism Reperfusion Injury - pathology Reperfusion Injury - prevention & control Tropical medicine
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