Isolation of human type 2 deiodinase gene promoter and characterization of a functional cyclic adenosine monophosphate response element

We analyzed the structure and function of the 5' flanking region of the human type 2 deiodinase (hD2) gene. Two major transcription start sites were identified at -470/-474 from the ATG. The 5' flanking region of hD2 gene efficiently directed transcription in transient transfection studies...

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