Adenoma-specific alterations of protein kinase C isozyme expression in Apc(MIN) mice

Members of the protein kinase C (PKC) family appear to play important roles in colorectal carcinogenesis. To investigate the potential involvement of PKC isozymes in adenomatous transformation induced by inactivation of the adenomatous polyposis coli (APC) gene product, we examined protein levels an...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2000-04, Vol.60 (8), p.2077
Hauptverfasser:	Klein, I K, Ritland, S R, Burgart, L J, Ziesmer, S C, Roche, P C, Gendler, S J, Karnes, Jr, W E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - enzymology Adenoma - genetics Adenoma - pathology Adenomatous Polyposis Coli - enzymology Adenomatous Polyposis Coli - genetics Adenomatous Polyposis Coli - pathology Animals Cell Nucleus - enzymology Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - pathology Gene Expression Regulation, Neoplastic Genes, APC - genetics Ileal Neoplasms - enzymology Ileal Neoplasms - genetics Ileal Neoplasms - pathology Ileum - cytology Ileum - enzymology Ileum - pathology Immunohistochemistry Intestinal Mucosa - cytology Intestinal Mucosa - enzymology Intestinal Mucosa - pathology Isoenzymes - chemistry Isoenzymes - genetics Isoenzymes - metabolism Mice Mice, Inbred C57BL Mice, Mutant Strains Protein Kinase C - chemistry Protein Kinase C - genetics Protein Kinase C - metabolism
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