Multiple-Drug Chemotherapy in the Management of Acute Lymphocytic Leukemia During Pregnancy

Acute leukemia associated with pregnancy is relatively uncommon, and because of the age distribution of patients with acute leukemia the majority have had acute granulocytic leukemia. Various combinations of chemotherapeutic agents are commonly employed now to obtain maximal benefit, related to diff...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Obstetrics and gynecology (New York. 1953) 1976-09, Vol.48 (3), p.324-327
Hauptverfasser: KRUEGER, JUDY A., DAVIS, RICHARD B., FIELD, CHARLES
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 327
container_issue 3
container_start_page 324
container_title Obstetrics and gynecology (New York. 1953)
container_volume 48
creator KRUEGER, JUDY A.
DAVIS, RICHARD B.
FIELD, CHARLES
description Acute leukemia associated with pregnancy is relatively uncommon, and because of the age distribution of patients with acute leukemia the majority have had acute granulocytic leukemia. Various combinations of chemotherapeutic agents are commonly employed now to obtain maximal benefit, related to differing pharmacologic activities of single agents. The present case documents the use of multiple cytotoxic drugs in the management of acute lymphocytic leukemia, with successful delivery of a normal infant. In this patient severe anemia and potentially teratogenic drugs did not appear to affect the fetus.
format Article
fullrecord <record><control><sourceid>pubmed_wolte</sourceid><recordid>TN_cdi_pubmed_primary_1065823</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1065823</sourcerecordid><originalsourceid>FETCH-LOGICAL-p2514-2f6ecb2ab0a2c3e9912be9ac96dcad7bd6cc9b065b7af57dabc26e783cae29c3</originalsourceid><addsrcrecordid>eNotUMlqwzAUFKUlTdN-QkE_IJAlW7aOIekGDu0hh0IP5kl-XhpvyBbBf1-X5DQzDAwzc0PWQRJLJqT8viVrzoVmcRKG9-RhHH8554HSckVWAVdRIuSa_Bx8M9VDg2zvfEl3Fbb9VKGDYaZ1RxdKD9BBiS12E-0LurV-QprO7VD1dp5qS1P0J2xroHvv6q6kXw7LDjo7P5K7ApoRn664IcfXl-PunaWfbx-7bcoGEQUhE4VCawQYDsJK1DoQBjVYrXILeWxyZa02S2ETQxHFORgrFMaJtIBCW7khz5fYwZsW82xwdQtuzq4bFz-8-Oe-mdCNp8af0WUVQjNV2fIJVyLiLNCx4npR7P-mUP4BbAxgpA</addsrcrecordid><sourcetype>Index Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Multiple-Drug Chemotherapy in the Management of Acute Lymphocytic Leukemia During Pregnancy</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>KRUEGER, JUDY A. ; DAVIS, RICHARD B. ; FIELD, CHARLES</creator><creatorcontrib>KRUEGER, JUDY A. ; DAVIS, RICHARD B. ; FIELD, CHARLES</creatorcontrib><description>Acute leukemia associated with pregnancy is relatively uncommon, and because of the age distribution of patients with acute leukemia the majority have had acute granulocytic leukemia. Various combinations of chemotherapeutic agents are commonly employed now to obtain maximal benefit, related to differing pharmacologic activities of single agents. The present case documents the use of multiple cytotoxic drugs in the management of acute lymphocytic leukemia, with successful delivery of a normal infant. In this patient severe anemia and potentially teratogenic drugs did not appear to affect the fetus.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>PMID: 1065823</identifier><language>eng</language><publisher>United States: The American College of Obstetricians and Gynecologists</publisher><subject>Adolescent ; Cyclophosphamide - therapeutic use ; Delivery, Obstetric ; Drug Therapy, Combination ; Female ; Humans ; Labor, Induced ; Leukemia, Lymphoid - drug therapy ; Mercaptopurine - therapeutic use ; Methotrexate - therapeutic use ; Prednisone - therapeutic use ; Pregnancy ; Pregnancy Complications, Hematologic - drug therapy ; Vincristine - therapeutic use</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1976-09, Vol.48 (3), p.324-327</ispartof><rights>1976 The American College of Obstetricians and Gynecologists</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1065823$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KRUEGER, JUDY A.</creatorcontrib><creatorcontrib>DAVIS, RICHARD B.</creatorcontrib><creatorcontrib>FIELD, CHARLES</creatorcontrib><title>Multiple-Drug Chemotherapy in the Management of Acute Lymphocytic Leukemia During Pregnancy</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>Acute leukemia associated with pregnancy is relatively uncommon, and because of the age distribution of patients with acute leukemia the majority have had acute granulocytic leukemia. Various combinations of chemotherapeutic agents are commonly employed now to obtain maximal benefit, related to differing pharmacologic activities of single agents. The present case documents the use of multiple cytotoxic drugs in the management of acute lymphocytic leukemia, with successful delivery of a normal infant. In this patient severe anemia and potentially teratogenic drugs did not appear to affect the fetus.</description><subject>Adolescent</subject><subject>Cyclophosphamide - therapeutic use</subject><subject>Delivery, Obstetric</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Humans</subject><subject>Labor, Induced</subject><subject>Leukemia, Lymphoid - drug therapy</subject><subject>Mercaptopurine - therapeutic use</subject><subject>Methotrexate - therapeutic use</subject><subject>Prednisone - therapeutic use</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Hematologic - drug therapy</subject><subject>Vincristine - therapeutic use</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotUMlqwzAUFKUlTdN-QkE_IJAlW7aOIekGDu0hh0IP5kl-XhpvyBbBf1-X5DQzDAwzc0PWQRJLJqT8viVrzoVmcRKG9-RhHH8554HSckVWAVdRIuSa_Bx8M9VDg2zvfEl3Fbb9VKGDYaZ1RxdKD9BBiS12E-0LurV-QprO7VD1dp5qS1P0J2xroHvv6q6kXw7LDjo7P5K7ApoRn664IcfXl-PunaWfbx-7bcoGEQUhE4VCawQYDsJK1DoQBjVYrXILeWxyZa02S2ETQxHFORgrFMaJtIBCW7khz5fYwZsW82xwdQtuzq4bFz-8-Oe-mdCNp8af0WUVQjNV2fIJVyLiLNCx4npR7P-mUP4BbAxgpA</recordid><startdate>197609</startdate><enddate>197609</enddate><creator>KRUEGER, JUDY A.</creator><creator>DAVIS, RICHARD B.</creator><creator>FIELD, CHARLES</creator><general>The American College of Obstetricians and Gynecologists</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>197609</creationdate><title>Multiple-Drug Chemotherapy in the Management of Acute Lymphocytic Leukemia During Pregnancy</title><author>KRUEGER, JUDY A. ; DAVIS, RICHARD B. ; FIELD, CHARLES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2514-2f6ecb2ab0a2c3e9912be9ac96dcad7bd6cc9b065b7af57dabc26e783cae29c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1976</creationdate><topic>Adolescent</topic><topic>Cyclophosphamide - therapeutic use</topic><topic>Delivery, Obstetric</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>Humans</topic><topic>Labor, Induced</topic><topic>Leukemia, Lymphoid - drug therapy</topic><topic>Mercaptopurine - therapeutic use</topic><topic>Methotrexate - therapeutic use</topic><topic>Prednisone - therapeutic use</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Hematologic - drug therapy</topic><topic>Vincristine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KRUEGER, JUDY A.</creatorcontrib><creatorcontrib>DAVIS, RICHARD B.</creatorcontrib><creatorcontrib>FIELD, CHARLES</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KRUEGER, JUDY A.</au><au>DAVIS, RICHARD B.</au><au>FIELD, CHARLES</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multiple-Drug Chemotherapy in the Management of Acute Lymphocytic Leukemia During Pregnancy</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1976-09</date><risdate>1976</risdate><volume>48</volume><issue>3</issue><spage>324</spage><epage>327</epage><pages>324-327</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><abstract>Acute leukemia associated with pregnancy is relatively uncommon, and because of the age distribution of patients with acute leukemia the majority have had acute granulocytic leukemia. Various combinations of chemotherapeutic agents are commonly employed now to obtain maximal benefit, related to differing pharmacologic activities of single agents. The present case documents the use of multiple cytotoxic drugs in the management of acute lymphocytic leukemia, with successful delivery of a normal infant. In this patient severe anemia and potentially teratogenic drugs did not appear to affect the fetus.</abstract><cop>United States</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>1065823</pmid><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0029-7844
ispartof Obstetrics and gynecology (New York. 1953), 1976-09, Vol.48 (3), p.324-327
issn 0029-7844
1873-233X
language eng
recordid cdi_pubmed_primary_1065823
source MEDLINE; Journals@Ovid Complete
subjects Adolescent
Cyclophosphamide - therapeutic use
Delivery, Obstetric
Drug Therapy, Combination
Female
Humans
Labor, Induced
Leukemia, Lymphoid - drug therapy
Mercaptopurine - therapeutic use
Methotrexate - therapeutic use
Prednisone - therapeutic use
Pregnancy
Pregnancy Complications, Hematologic - drug therapy
Vincristine - therapeutic use
title Multiple-Drug Chemotherapy in the Management of Acute Lymphocytic Leukemia During Pregnancy
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T19%3A38%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_wolte&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Multiple-Drug%20Chemotherapy%20in%20the%20Management%20of%20Acute%20Lymphocytic%20Leukemia%20During%20Pregnancy&rft.jtitle=Obstetrics%20and%20gynecology%20(New%20York.%201953)&rft.au=KRUEGER,%20JUDY%20A.&rft.date=1976-09&rft.volume=48&rft.issue=3&rft.spage=324&rft.epage=327&rft.pages=324-327&rft.issn=0029-7844&rft.eissn=1873-233X&rft_id=info:doi/&rft_dat=%3Cpubmed_wolte%3E1065823%3C/pubmed_wolte%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/1065823&rfr_iscdi=true