Apoptosis in Vascular Endothelial Cells Caused by Serum Deprivation, Oxidative Stress and Transforming Growth Factor-β

Vascular endothelial cell apoptosis has previously been shown to play a role in the pathogenesis of hypertension-induced vessel deletion and damage. In the present in vitro study we analyse several possible relevant causative factors of vascular endothelial cell apoptosis, namely, serum deprivation...

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Veröffentlicht in:	Endothelium (New York, N.Y.) N.Y.), 1999, Vol.7 (1), p.35-49
Hauptverfasser:	Hogg, N., Browning, J., Howard, T., Winterford, C., Fitzpatrick, D., Gobé, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Cattle Cell Line Cell Size Culture Media, Serum-Free - pharmacology endothelium Endothelium, Vascular - cytology Endothelium, Vascular - physiopathology Endothelium, Vascular - ultrastructure hypoxia Immunohistochemistry In Situ Nick-End Labeling Microscopy, Electron Mitosis - drug effects oxidative stress Oxidative Stress - physiology Polymerase Chain Reaction Proliferating Cell Nuclear Antigen - analysis serum deprivation Staining and Labeling TGF-β1 Transforming Growth Factor beta - genetics Transforming Growth Factor beta - pharmacology
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