N-Acetyltransferase 1 Genetic Polymorphism, Cigarette Smoking, Well-Done Meat Intake, and Breast Cancer Risk

N -Acetyltransferase 1 (NAT1), encoded by the polymorphic NAT1 gene, has been shown to be one of the major enzymes in human breast tissue that activates aromatic and heterocyclic amines. Humans are mainly exposed to these carcinogens through cigarette smoking and consumption of well-done meat. To te...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 1999-03, Vol.8 (3), p.233
Hauptverfasser:	Zheng, W, Deitz, A C, Campbell, D R, Wen, W Q, Cerhan, J R, Sellers, T A, Folsom, A R, Hein, D W
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles Amines - metabolism Arylamine N-Acetyltransferase - genetics Breast - enzymology Breast Neoplasms - enzymology Breast Neoplasms - epidemiology Breast Neoplasms - genetics Carcinogens - metabolism Case-Control Studies Cohort Studies Confidence Intervals Cooking DNA - genetics Feeding Behavior Female Gene Frequency Humans Iowa - epidemiology Isoenzymes - genetics Meat Middle Aged Multivariate Analysis Odds Ratio Polymorphism, Genetic - genetics Postmenopause Prospective Studies Risk Factors Smoking - epidemiology
Online-Zugang:	Volltext
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