Cytotoxicity evaluation of multipurpose contact lens solutions using an in vitro test battery

Many in vitro alternatives to eye irritation testing are not mechanism-specific and do not employ ocular cell lines. We have developed an effective and reliable test battery that reveals toxicity mechanisms of contact lens solutions on cell metabolism and proliferation. Cytotoxicity endpoints were q...

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Veröffentlicht in:	The CLAO journal 1999, Vol.25 (1), p.28-35
Hauptverfasser:	PHAM, X. T, HUFF, J. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cattle Cell Division - drug effects Cell Survival - drug effects Cells, Cultured Coloring Agents Contact Lens Solutions - toxicity Diseases of the eye Epithelium, Corneal - cytology Epithelium, Corneal - drug effects Epithelium, Corneal - metabolism Glycolysis - drug effects Lactic Acid - metabolism Medical sciences Oxazines Oxidation-Reduction Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Xanthenes
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