Barium Toxicity After Exposure to Contaminated Contrast Solution — Goias State, Brazil, 2003
Barium-containing contrast solutions are commonly used in radiologic studies. On May 22, 2003, three patients at radiology clinics in Goias State, Brazil, were hospitalized after ingesting such solutions; two persons died within 24 hours of hospitalization. Exposure occurred during radiologic examin...
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| Veröffentlicht in: | MMWR. Morbidity and mortality weekly report 2003-10, Vol.52 (43), p.1047-1048 |
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| creator | Silva, RF Santi, LQ Santos, AA Freitas, F Dias, MF Bezerra, PA Daufenbach, LZ Nascimento, CP Carmo, EH da Silva, JB Hatch, DL |
| description | Barium-containing contrast solutions are commonly used in radiologic studies. On May 22, 2003, three patients at radiology clinics in Goias State, Brazil, were hospitalized after ingesting such solutions; two persons died within 24 hours of hospitalization. Exposure occurred during radiologic examination of the upper or lower gastrointestinal tract. An investigation was conducted by municipal and state public health authorities with assistance from the Ministry of Health's National Agency for Sanitary Surveillance (ANVISA) and Brazil's Field Epidemiology Training Program (FETP), known locally as EPISUS. This report summarizes the results of that investigation, which found that 44 persons had suspected barium toxicity, nine of whom died. Eight of the nine deaths were linked to a single lot of brand A contrast solution. A national recall was announced on May 23, and the manufacturing facility was inspected and closed. Clinicians should be alert for signs of barium toxicity in patients in the hours after administration of contrast solutions during radiologic studies. |
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On May 22, 2003, three patients at radiology clinics in Goias State, Brazil, were hospitalized after ingesting such solutions; two persons died within 24 hours of hospitalization. Exposure occurred during radiologic examination of the upper or lower gastrointestinal tract. An investigation was conducted by municipal and state public health authorities with assistance from the Ministry of Health's National Agency for Sanitary Surveillance (ANVISA) and Brazil's Field Epidemiology Training Program (FETP), known locally as EPISUS. This report summarizes the results of that investigation, which found that 44 persons had suspected barium toxicity, nine of whom died. Eight of the nine deaths were linked to a single lot of brand A contrast solution. A national recall was announced on May 23, and the manufacturing facility was inspected and closed. Clinicians should be alert for signs of barium toxicity in patients in the hours after administration of contrast solutions during radiologic studies.</description><identifier>ISSN: 0149-2195</identifier><identifier>EISSN: 1545-861X</identifier><identifier>PMID: 14586298</identifier><language>eng</language><publisher>United States: Centers for Disease Control and Prevention</publisher><subject>Barium ; Barium Compounds - poisoning ; Brazil - epidemiology ; Chemical hazards ; Chemicals ; Contamination ; Contrast Media - poisoning ; Environmental surveillance ; Epidemiology ; Health aspects ; Health surveillance ; Humans ; Investigations ; Occupational health and safety ; Patient assessment ; Poisoning - epidemiology ; Poisoning, Accidental ; Public health ; Radiology ; Radiology, Medical ; Solutions ; Surveillance ; Symptoms ; Toxicity</subject><ispartof>MMWR. Morbidity and mortality weekly report, 2003-10, Vol.52 (43), p.1047-1048</ispartof><rights>COPYRIGHT 2003 U.S. Government Printing Office</rights><rights>Copyright U.S. Center for Disease Control Oct 31, 2003</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/23314812$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/23314812$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14586298$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silva, RF</creatorcontrib><creatorcontrib>Santi, LQ</creatorcontrib><creatorcontrib>Santos, AA</creatorcontrib><creatorcontrib>Freitas, F</creatorcontrib><creatorcontrib>Dias, MF</creatorcontrib><creatorcontrib>Bezerra, PA</creatorcontrib><creatorcontrib>Daufenbach, LZ</creatorcontrib><creatorcontrib>Nascimento, CP</creatorcontrib><creatorcontrib>Carmo, EH</creatorcontrib><creatorcontrib>da Silva, JB</creatorcontrib><creatorcontrib>Hatch, DL</creatorcontrib><creatorcontrib>Centers for Disease Control and Prevention (CDC)</creatorcontrib><title>Barium Toxicity After Exposure to Contaminated Contrast Solution — Goias State, Brazil, 2003</title><title>MMWR. Morbidity and mortality weekly report</title><addtitle>MMWR Morb Mortal Wkly Rep</addtitle><description>Barium-containing contrast solutions are commonly used in radiologic studies. On May 22, 2003, three patients at radiology clinics in Goias State, Brazil, were hospitalized after ingesting such solutions; two persons died within 24 hours of hospitalization. Exposure occurred during radiologic examination of the upper or lower gastrointestinal tract. An investigation was conducted by municipal and state public health authorities with assistance from the Ministry of Health's National Agency for Sanitary Surveillance (ANVISA) and Brazil's Field Epidemiology Training Program (FETP), known locally as EPISUS. This report summarizes the results of that investigation, which found that 44 persons had suspected barium toxicity, nine of whom died. Eight of the nine deaths were linked to a single lot of brand A contrast solution. A national recall was announced on May 23, and the manufacturing facility was inspected and closed. Clinicians should be alert for signs of barium toxicity in patients in the hours after administration of contrast solutions during radiologic studies.</description><subject>Barium</subject><subject>Barium Compounds - poisoning</subject><subject>Brazil - epidemiology</subject><subject>Chemical hazards</subject><subject>Chemicals</subject><subject>Contamination</subject><subject>Contrast Media - poisoning</subject><subject>Environmental surveillance</subject><subject>Epidemiology</subject><subject>Health aspects</subject><subject>Health surveillance</subject><subject>Humans</subject><subject>Investigations</subject><subject>Occupational health and safety</subject><subject>Patient assessment</subject><subject>Poisoning - epidemiology</subject><subject>Poisoning, Accidental</subject><subject>Public health</subject><subject>Radiology</subject><subject>Radiology, Medical</subject><subject>Solutions</subject><subject>Surveillance</subject><subject>Symptoms</subject><subject>Toxicity</subject><issn>0149-2195</issn><issn>1545-861X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkUtOwzAQQCMEglI4AshsWBHkT5zYy1LxkyqxaJFYEbnJpBglcbEdibLiEJyQk2BoQYDqWVgz8-a_EfUIT3gsUnK3GfUwSWRMieQ70a5zj_jzMbwd7ZCEi5RK0Yvuz5TVXYMm5lkX2i_QoPJg0fnz3LjOAvIGDU3rVaNb5aH8UqxyHo1N3XltWvT--oYujVYOjX1ATtCZVS-6PkE0FNuLtipVO9hf_f3o9uJ8MryKRzeX18PBKJ4xQnxcUiYlkZQmHLKEZbIiUNC0yCrBSNBBJIJTSFTKSqLSYjpNwiCcphwTiauK9aOjZd65NU8dOJ9bmBvrXU5xSIdTmgbm-B_TaFdAXasWTOdyIjCjnMkAxktwpmrIdVuZMHIxgxasqk0LlQ7mASGYZ1QIHvjTNXyQEhpdrA04_hXwAKr2D261T_cXPFy13E0bKPO51Y2yi_z7fgE4WAKPzhv746csrE0Qyj4AN6-dUA</recordid><startdate>20031031</startdate><enddate>20031031</enddate><creator>Silva, RF</creator><creator>Santi, LQ</creator><creator>Santos, AA</creator><creator>Freitas, F</creator><creator>Dias, MF</creator><creator>Bezerra, PA</creator><creator>Daufenbach, LZ</creator><creator>Nascimento, CP</creator><creator>Carmo, EH</creator><creator>da Silva, JB</creator><creator>Hatch, DL</creator><general>Centers for Disease Control and Prevention</general><general>U.S. Government Printing Office</general><general>U.S. Center for Disease Control</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T2</scope><scope>7U2</scope><scope>C1K</scope><scope>0-V</scope><scope>3V.</scope><scope>4T-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88F</scope><scope>88J</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M1Q</scope><scope>M2O</scope><scope>M2R</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>S0X</scope></search><sort><creationdate>20031031</creationdate><title>Barium Toxicity After Exposure to Contaminated Contrast Solution — Goias State, Brazil, 2003</title><author>Silva, RF ; Santi, LQ ; Santos, AA ; Freitas, F ; Dias, MF ; Bezerra, PA ; Daufenbach, LZ ; Nascimento, CP ; Carmo, EH ; da Silva, JB ; Hatch, DL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g311t-d2399192245e74379f1ec26c7f831437e84852e4a63d1a6cbb403052650190ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Barium</topic><topic>Barium Compounds - poisoning</topic><topic>Brazil - epidemiology</topic><topic>Chemical hazards</topic><topic>Chemicals</topic><topic>Contamination</topic><topic>Contrast Media - poisoning</topic><topic>Environmental surveillance</topic><topic>Epidemiology</topic><topic>Health aspects</topic><topic>Health surveillance</topic><topic>Humans</topic><topic>Investigations</topic><topic>Occupational health and safety</topic><topic>Patient assessment</topic><topic>Poisoning - epidemiology</topic><topic>Poisoning, Accidental</topic><topic>Public health</topic><topic>Radiology</topic><topic>Radiology, Medical</topic><topic>Solutions</topic><topic>Surveillance</topic><topic>Symptoms</topic><topic>Toxicity</topic><toplevel>online_resources</toplevel><creatorcontrib>Silva, RF</creatorcontrib><creatorcontrib>Santi, LQ</creatorcontrib><creatorcontrib>Santos, AA</creatorcontrib><creatorcontrib>Freitas, F</creatorcontrib><creatorcontrib>Dias, MF</creatorcontrib><creatorcontrib>Bezerra, PA</creatorcontrib><creatorcontrib>Daufenbach, LZ</creatorcontrib><creatorcontrib>Nascimento, CP</creatorcontrib><creatorcontrib>Carmo, EH</creatorcontrib><creatorcontrib>da Silva, JB</creatorcontrib><creatorcontrib>Hatch, DL</creatorcontrib><creatorcontrib>Centers for Disease Control and Prevention (CDC)</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Military Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Military Database</collection><collection>Research Library</collection><collection>Social Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><jtitle>MMWR. Morbidity and mortality weekly report</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silva, RF</au><au>Santi, LQ</au><au>Santos, AA</au><au>Freitas, F</au><au>Dias, MF</au><au>Bezerra, PA</au><au>Daufenbach, LZ</au><au>Nascimento, CP</au><au>Carmo, EH</au><au>da Silva, JB</au><au>Hatch, DL</au><aucorp>Centers for Disease Control and Prevention (CDC)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Barium Toxicity After Exposure to Contaminated Contrast Solution — Goias State, Brazil, 2003</atitle><jtitle>MMWR. Morbidity and mortality weekly report</jtitle><addtitle>MMWR Morb Mortal Wkly Rep</addtitle><date>2003-10-31</date><risdate>2003</risdate><volume>52</volume><issue>43</issue><spage>1047</spage><epage>1048</epage><pages>1047-1048</pages><issn>0149-2195</issn><eissn>1545-861X</eissn><abstract>Barium-containing contrast solutions are commonly used in radiologic studies. On May 22, 2003, three patients at radiology clinics in Goias State, Brazil, were hospitalized after ingesting such solutions; two persons died within 24 hours of hospitalization. Exposure occurred during radiologic examination of the upper or lower gastrointestinal tract. An investigation was conducted by municipal and state public health authorities with assistance from the Ministry of Health's National Agency for Sanitary Surveillance (ANVISA) and Brazil's Field Epidemiology Training Program (FETP), known locally as EPISUS. This report summarizes the results of that investigation, which found that 44 persons had suspected barium toxicity, nine of whom died. Eight of the nine deaths were linked to a single lot of brand A contrast solution. A national recall was announced on May 23, and the manufacturing facility was inspected and closed. Clinicians should be alert for signs of barium toxicity in patients in the hours after administration of contrast solutions during radiologic studies.</abstract><cop>United States</cop><pub>Centers for Disease Control and Prevention</pub><pmid>14586298</pmid><tpages>2</tpages></addata></record> |
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| identifier | ISSN: 0149-2195 |
| ispartof | MMWR. Morbidity and mortality weekly report, 2003-10, Vol.52 (43), p.1047-1048 |
| issn | 0149-2195 1545-861X |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; JSTOR Archive Collection A-Z Listing |
| subjects | Barium Barium Compounds - poisoning Brazil - epidemiology Chemical hazards Chemicals Contamination Contrast Media - poisoning Environmental surveillance Epidemiology Health aspects Health surveillance Humans Investigations Occupational health and safety Patient assessment Poisoning - epidemiology Poisoning, Accidental Public health Radiology Radiology, Medical Solutions Surveillance Symptoms Toxicity |
| title | Barium Toxicity After Exposure to Contaminated Contrast Solution — Goias State, Brazil, 2003 |
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