Effects of column inner diameter and packed bed heterogeneities on chromatographic performance
Reduced flow rates are also advantageous when attempting to improve the limits of detection (LOD) of methods that couple high performance liquid chromatography (HPLC) to electrospray ionization mass spectrometry (ESI-MS) (5). In capillaries, the correlation of column packing parameters and chromatog...
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Veröffentlicht in: | LC GC North America 2016-06, Vol.34 (6), p.388 |
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description | Reduced flow rates are also advantageous when attempting to improve the limits of detection (LOD) of methods that couple high performance liquid chromatography (HPLC) to electrospray ionization mass spectrometry (ESI-MS) (5). In capillaries, the correlation of column packing parameters and chromatographic performance to the morphological structures of packed beds suggests possible means to improve the intrinsic efficiencies of columns by improving radial homogeneity and reducing transcolumn eddy dispersion (6). |
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source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Business Source Complete; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
subjects | Atoms & subatomic particles Chromatography Efficiency Flow velocity Morphology Particle size Velocity |
title | Effects of column inner diameter and packed bed heterogeneities on chromatographic performance |
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