Investigation of various impurities in febuxostat

Febuxostat is a novel, non-purine, selective inhibitor of xanthine oxidase for hyperuricemia in patients with gout. The drug reduces uric acid production by inhibiting the activity of xanthine oxidase, an enzyme that, in the last step of purine metabolism, converts xanthine to uric acid. Research ha...

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Veröffentlicht in:	Pharmaceutical Technology 2014-09, Vol.38 (9), p.38
Hauptverfasser:	Lahoti, Anand M, Ravi, Ponnaiah, Kumar, Neela Praveen, Innareddy, V, Deepthi, P.S, Shanmugam, V, Rao, M. Sudhakar, Reddy, Vivekananda
Format:	Magazinearticle
Sprache:	eng
Schlagworte:	By products Chemical synthesis Chromatography Clinical trials Fourier transforms Inhibitor drugs Methods NMR Nuclear magnetic resonance Potassium Product development Rheumatism Studies Uric acid
Online-Zugang:	Volltext
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