Preparation and in vitro evaluation of self-nanoemulsifying drug delivery systems (SNEDDS) containing clotrimazole

This study sought to formulate and evaluate a self-nanoemulsified drug delivery system (SNEDDS) for clotrimazole (CT), a poorly water-soluble antimycotic drug, used in vaginal delivery. SNEDDS was developed to increase the CT dissolution rate, solubility, and ultimately bioavailability. The solubili...

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Veröffentlicht in:	Drug discoveries & therapeutics 2010-10, Vol.4 (5), p.373-379
Hauptverfasser:	Kassem, A A, Marzouk, M A, Ammar, A A, Elosaily, G H
Format:	Artikel
Sprache:	eng
Schlagworte:	Clotrimazole Drug Delivery Systems Emulsions - chemistry Nanoparticles Solubility Surface-Active Agents - chemistry
Online-Zugang:	Volltext
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