Flowers from Kalanchoe pinnata are a Rich Source of T Cell-Suppressive Flavonoids

The chemical composition and immunosuppressive potential of the flowers from Kalanchoe pinnata (Crassulaceae) were investigated. We found that the aqueous flower extract was more active than the leaf extract in inhibiting murine T cell mitogenesis in vitro. Flavonoids isolated from the flower extrac...

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Veröffentlicht in:	Natural product communications 2012-02, Vol.7 (2), p.175-178
Hauptverfasser:	Coutinho, Marcela A. S., Muzitano, Michelle F., Cruz, Elaine A., Bergonzi, Maria C., Kaiser, Carlos R., Tinoco, Luzineide W., Bilia, Anna R., Vincieri, Franco F., Rossi-Bergmann, Bartira, Costa, Sônia S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Polarity Cell Proliferation - drug effects Cytokines - genetics Cytokines - metabolism Flavonoids - chemistry Flavonoids - pharmacology Flowers - chemistry Gene Expression Regulation - drug effects Immunosuppressive Agents - chemistry Immunosuppressive Agents - pharmacology Kalanchoe - chemistry Lymph Nodes - cytology Macrophages - drug effects Macrophages - metabolism Mice Mice, Inbred BALB C T-Lymphocytes - drug effects
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