In vitro and in vivo characterization of amorphous, nanocrystalline, and crystalline ziprasidone formulations

Ziprasidone, commercially available as Geodon® capsules, is an atypical antipsychotic used in the treatment of schizophrenia and bipolar disorder. It is a BCS Class II drug that shows up to a 2-fold increase in absorption in the presence of food. Because compliance is a major issue in this patient p...

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