Myocardial migration by fibroblast progenitor cells is blood pressure dependent in a model of angII myocardial fibrosis

Activation of the renin-angiotensin system (RAS) is thought to promote myocardial fibrosis. However, it is unclear whether this physiological fibrotic response results from chronic hemodynamic stress or from direct cellular signaling. Male C57B/6 mice were randomly assigned to receive angiotensin II...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hypertension research 2012-04, Vol.35 (4), p.449-456
Hauptverfasser:	Rosin, Nicole L, Sopel, Mryanda, Falkenham, Alec, Myers, Tanya L, Légaré, Jean-Francois
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone - blood Angiotensin II - pharmacology Animals Blood Pressure - drug effects Blood Pressure - physiology Cell Movement - drug effects Cell Movement - physiology Collagen - metabolism Fibroblasts - drug effects Fibroblasts - metabolism Fibroblasts - pathology Fibrosis Heart - drug effects Hypertension - chemically induced Hypertension - metabolism Hypertension - pathology Male Mice Myocardium - metabolism Myocardium - pathology Renin-Angiotensin System - drug effects Stem Cells - drug effects Stem Cells - metabolism Stem Cells - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!