Single-nucleotide polymorphism array coupled with multiple displacement amplification: Accuracy and spatial resolution for analysis of chromosome copy numbers in few cells

When coupled with multiple displacement amplification (MDA), microarray‐based comparative genomic intensity allows detection of chromosome copy number aberrations even in single or few cells, but the actual performance of the system and their influencing factors have not been well defined. Here, usi...

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Veröffentlicht in:Biotechnology and applied biochemistry 2012-01, Vol.59 (1), p.35-44
Hauptverfasser: Ling, Jiawei, Deng, Yu, Long, Xiaolin, Liu, Jianqiao, Du, Hongzi, Cao, Baoqiang, Xu, Kangpu
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Sprache:eng
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