signature of six genes highlights defects on cell growth and specific metabolic pathways in murine and human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) represents a major health problem as it afflicts an increasing number of patients worldwide. Albeit most of the risk factors for HCC are known, this is a deadly syndrome with a life expectancy at the time of diagnosis of less than 1 year. Definition of the molecular pr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Functional & integrative genomics 2011-09, Vol.11 (3), p.419-429
Hauptverfasser:	Schröder, Paul C, Segura, Víctor, Riezu, José Ignacio, Sangro, Bruno, Mato, José M, Prieto, Jesús, Santamaría, Enrique, Corrales, Fernando J
Format:	Artikel
Sprache:	eng
Schlagworte:	acyl coenzyme A Acyl-CoA dehydrogenase Adult Aged Animal Genetics and Genomics Animal models Animals biochemical pathways Biochemistry Bioinformatics Biological and medical sciences Biomarkers, Tumor - blood Biomedical and Life Sciences Carbon Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Case-Control Studies Cell Adhesion Molecules - blood Cell Biology Cell growth Cell Proliferation Cellular biology Cytoskeleton data collection fatty acid metabolism Fatty acids Female Fundamental and applied biological sciences. Psychology Gene Expression Profiling gene expression regulation Gene Knockout Techniques General aspects Genes Genes, Neoplasm Glucose Hepatocellular carcinoma hepatoma Homeostasis Humans Life Sciences Life span Liver Liver cancer Liver Cirrhosis - genetics Liver Cirrhosis - metabolism Liver Cirrhosis - pathology Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver Neoplasms, Experimental - genetics Liver Neoplasms, Experimental - metabolism Liver Neoplasms, Experimental - pathology longevity Male Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Metabolic Networks and Pathways - genetics Metabolic pathways Methionine adenosyltransferase Methionine Adenosyltransferase - genetics Mice Mice, Inbred C57BL Mice, Knockout Microbial Genetics and Genomics Microfilament Proteins - blood Middle Aged new methods Oligonucleotide Array Sequence Analysis Original Paper patients Phosphoglucomutase Phosphoproteins - blood Plant Genetics and Genomics Polymerase chain reaction Probes quantitative polymerase chain reaction reverse transcriptase polymerase chain reaction Risk factors Transformation vasodilator-stimulated phosphoprotein
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!