Copper binding traps the folded state of the SCO protein from Bacillus subtilis

The SCO protein from the aerobic bacterium Bacillus subtilis (BsSCO) is involved in the assembly of the cytochrome c oxidase complex, and specifically with the CuA center. BsSCO has been proposed to play various roles in CuA assembly including, the direct delivery of copper ions to the CuA site, and...

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Veröffentlicht in:	Biochimica et biophysica acta 2012-02, Vol.1824 (2), p.292-302
Hauptverfasser:	Lai, Mark, Yam, Katherine C., Andrews, Diann, Hill, Bruce C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis Bacillus subtilis - metabolism bacteria Bacterial Proteins - metabolism copper Copper - metabolism Copper binding CuA assembly cysteine Cysteine - metabolism Cytochrome c oxidase denaturation Electron Transport Complex IV - metabolism Kinetics Ligands Membrane Proteins - metabolism oxidation Oxidation-Reduction Protein Binding Protein Conformation Protein Folding Protein folding kinetics Protein oxidation Spectrometry, Fluorescence Thermodynamics Urea
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