Developmental Genetics and New Sequencing Technologies: The Rise of Nonmodel Organisms

Much of developmental biology in the past decades has been driven by forward genetic studies in a few model organisms. We review recent work with relatives of these species, motivated by a desire to understand the evolutionary and ecological context for morphological innovation. Unfortunately, despi...

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Veröffentlicht in:Developmental cell 2011-07, Vol.21 (1), p.65-76
Hauptverfasser: Rowan, Beth A., Weigel, Detlef, Koenig, Daniel
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container_title Developmental cell
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creator Rowan, Beth A.
Weigel, Detlef
Koenig, Daniel
description Much of developmental biology in the past decades has been driven by forward genetic studies in a few model organisms. We review recent work with relatives of these species, motivated by a desire to understand the evolutionary and ecological context for morphological innovation. Unfortunately, despite a number of shining examples, progress in nonmodel systems has often been slow. The current revolution in DNA sequencing has, however, enormous potential in extending the reach of genetics. We discuss how developmental biology will benefit from these advances, particularly by increasing the universe of study species.
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subjects Animals
Biological and medical sciences
Cell differentiation, maturation, development, hematopoiesis
Cell physiology
Developmental Biology - methods
Evolution, Molecular
Fundamental and applied biological sciences. Psychology
Genomics
Humans
Models, Animal
Molecular and cellular biology
Sequence Analysis, DNA - methods
title Developmental Genetics and New Sequencing Technologies: The Rise of Nonmodel Organisms
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