The centrosome and spindle as a ribonucleoprotein complex
The notion of nucleic acids in the spindle, and particularly, the centrosome has a long history of inquiry, doubt, and debate. However, the association of specific RNAs with these structures is now confirmed by several investigators. What their presence means for the assembly, function, and evolutio...
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| Veröffentlicht in: | Chromosome research 2011-04, Vol.19 (3), p.367-376 |
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| container_title | Chromosome research |
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| creator | Alliegro, Mark C. |
| description | The notion of nucleic acids in the spindle, and particularly, the centrosome has a long history of inquiry, doubt, and debate. However, the association of specific RNAs with these structures is now confirmed by several investigators. What their presence means for the assembly, function, and evolution of the cell division apparatus is not known; but with newly available information and probes, these are questions that can finally be addressed. The present article summarizes the history of this field, what we know about the molecules in question, and in light of these findings, emphasizes the need to view the cell division apparatus for what it is by definition, a ribonucleoprotein complex. |
| doi_str_mv | 10.1007/s10577-011-9186-7 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0967-3849 |
| ispartof | Chromosome research, 2011-04, Vol.19 (3), p.367-376 |
| issn | 0967-3849 1573-6849 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Animal Genetics and Genomics Animals Biomedical and Life Sciences Cell Biology Cell division Centrosome - metabolism Human Genetics Humans Life Sciences Nucleic Acids - metabolism Plant Genetics and Genomics Ribonucleic acid Ribonucleoproteins - chemistry Ribonucleoproteins - metabolism RNA Spindle Apparatus - metabolism |
| title | The centrosome and spindle as a ribonucleoprotein complex |
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