Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women
Background/Objectives: Significance of dietary fatty acids on bone health is not clear, and the evidence is controversial. This study aimed to investigate the relationship between dietary polyunsaturated fatty acids (PUFAs) and bone mineral density (BMD) among elderly women. Subjects/Methods: Subjec...
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| Veröffentlicht in: | European journal of clinical nutrition 2012-04, Vol.66 (4), p.496-503 |
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| container_title | European journal of clinical nutrition |
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| creator | Järvinen, R Tuppurainen, M Erkkilä, A T Penttinen, P Kärkkäinen, M Salovaara, K Jurvelin, J S Kröger, H |
| description | Background/Objectives:
Significance of dietary fatty acids on bone health is not clear, and the evidence is controversial. This study aimed to investigate the relationship between dietary polyunsaturated fatty acids (PUFAs) and bone mineral density (BMD) among elderly women.
Subjects/Methods:
Subjects (
n
=554) were drawn from the Kuopio OSTPRE Fracture Prevention Study. At baseline they filled a 3-day food record and a questionnaire on lifestyle factors, diseases and medications. BMD was measured at lumbar spine (L2–L4), femoral neck and total body by dual energy X-ray absorptiometry at baseline and after 3 years. The associations between dietary fatty acids and BMD were analyzed by a linear mixed model adjusting for potential dietary and non-dietary confounders.
Results:
Our findings suggested a positive relationship between the dietary PUFAs and BMD at lumbar spine and in total body but not at femoral neck. Further analyses revealed that these results were due to associations among the women without hormone therapy (HT) at baseline. Among them, the intake of total PUFAs as well the intakes of linoleic and linolenic acids and total n-3 and n-6 fatty acids were significantly associated with BMD at lumbar spine;
P
for trend over the quartiles ranged between 0.013 and 0.001. Similarly, significant associations were demonstrated for total body BMD and fatty acids with an exception of total PUFA. No significant associations were found among women with HT at baseline.
Conclusions:
Our findings among elderly women without HT support the suggested beneficial effect of dietary PUFAs on bone health. |
| doi_str_mv | 10.1038/ejcn.2011.188 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_968102000</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A285994740</galeid><sourcerecordid>A285994740</sourcerecordid><originalsourceid>FETCH-LOGICAL-c624t-8f2605578c970ff1acedf8941891bdaf9ec38d8fb9709a037009a15b50d56b573</originalsourceid><addsrcrecordid>eNp9kkuPFCEUhStG47SjS7eGOPGxqRYoqIJlZ-IrmcSNbq1QPLrpUNAClUn_e6mxtdWUhgUJ57v3wuFU1VME1wg27I3eS7_GEKE1YuxetUKka2vaEni_WkFOSd1A2F1Uj1LaQ1jEDj-sLjBGqMGEr6qvm5SCtCLb4BMIBiirs4hHcAjuOPkk8hRF1goYkfMRCGlVArc278AQvAaj9ToKB5T2yRbdeqCd0tEdwW0YtX9cPTDCJf3ktF9WX969_Xz9ob759P7j9eamli0muWYGt5DSjkneQWOQkFoZxgliHA1KGK5lwxQzQ5G5gE0Hy4boQKGi7UC75rJ69aPvIYZvk065H22S2jnhdZhSz1uGIIYQFvL1f0kEeUNIgWlBn_-F7sMUfXlH6ddwwlmDCnT1Lwi3BLcUYdKcqa1wurfehByFnCf3G8wo56Qj893qBWqr7zwudhtbjv_g1wt8WUqPVi4WvPytYKeFy7sU3HT3-4s3kTGkFLXpD9GOJRfFn37OXT_nrp9z15fcFf7ZyYVpGLX6Rf8MWgFenACRpHAmCi9tOnO0bee_PT8pFclvdTzbuTz5O9vf6-s</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2642651243</pqid></control><display><type>article</type><title>Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women</title><source>MEDLINE</source><source>SpringerLink Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Järvinen, R ; Tuppurainen, M ; Erkkilä, A T ; Penttinen, P ; Kärkkäinen, M ; Salovaara, K ; Jurvelin, J S ; Kröger, H</creator><creatorcontrib>Järvinen, R ; Tuppurainen, M ; Erkkilä, A T ; Penttinen, P ; Kärkkäinen, M ; Salovaara, K ; Jurvelin, J S ; Kröger, H</creatorcontrib><description>Background/Objectives:
Significance of dietary fatty acids on bone health is not clear, and the evidence is controversial. This study aimed to investigate the relationship between dietary polyunsaturated fatty acids (PUFAs) and bone mineral density (BMD) among elderly women.
Subjects/Methods:
Subjects (
n
=554) were drawn from the Kuopio OSTPRE Fracture Prevention Study. At baseline they filled a 3-day food record and a questionnaire on lifestyle factors, diseases and medications. BMD was measured at lumbar spine (L2–L4), femoral neck and total body by dual energy X-ray absorptiometry at baseline and after 3 years. The associations between dietary fatty acids and BMD were analyzed by a linear mixed model adjusting for potential dietary and non-dietary confounders.
Results:
Our findings suggested a positive relationship between the dietary PUFAs and BMD at lumbar spine and in total body but not at femoral neck. Further analyses revealed that these results were due to associations among the women without hormone therapy (HT) at baseline. Among them, the intake of total PUFAs as well the intakes of linoleic and linolenic acids and total n-3 and n-6 fatty acids were significantly associated with BMD at lumbar spine;
P
for trend over the quartiles ranged between 0.013 and 0.001. Similarly, significant associations were demonstrated for total body BMD and fatty acids with an exception of total PUFA. No significant associations were found among women with HT at baseline.
Conclusions:
Our findings among elderly women without HT support the suggested beneficial effect of dietary PUFAs on bone health.</description><identifier>ISSN: 0954-3007</identifier><identifier>EISSN: 1476-5640</identifier><identifier>DOI: 10.1038/ejcn.2011.188</identifier><identifier>PMID: 22113249</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject><![CDATA[Absorptiometry, Photon - methods ; Aged ; Aged women ; alpha-Linolenic Acid - administration & dosage ; Biological and medical sciences ; Body Mass Index ; Bone density ; Bone Density - drug effects ; Bone mineral density ; Bones ; Calcium, Dietary - administration & dosage ; Clinical Nutrition ; Density ; Diet ; Dietary Fats - administration & dosage ; Dual energy X-ray absorptiometry ; Epidemiology ; Fatty acids ; Fatty Acids, Unsaturated - administration & dosage ; Feeding. Feeding behavior ; Female ; Femur ; Femur Neck - drug effects ; Fish oils ; Fundamental and applied biological sciences. Psychology ; Health aspects ; Humans ; Internal Medicine ; Investigative techniques, diagnostic techniques (general aspects) ; Linoleic Acid - administration & dosage ; Lumbar Vertebrae - drug effects ; Medical sciences ; Medicine ; Medicine & Public Health ; Metabolic Diseases ; Older people ; original-article ; Osteoarticular system. Muscles ; Osteoporosis ; Physiological aspects ; Polyunsaturated fatty acids ; Prevention ; Public Health ; Quartiles ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Spine ; Spine (lumbar) ; Surveys and Questionnaires ; Unsaturated fatty acids ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Womens health]]></subject><ispartof>European journal of clinical nutrition, 2012-04, Vol.66 (4), p.496-503</ispartof><rights>Macmillan Publishers Limited 2012</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2012 Nature Publishing Group</rights><rights>Macmillan Publishers Limited 2012.</rights><rights>Copyright Nature Publishing Group Apr 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c624t-8f2605578c970ff1acedf8941891bdaf9ec38d8fb9709a037009a15b50d56b573</citedby><cites>FETCH-LOGICAL-c624t-8f2605578c970ff1acedf8941891bdaf9ec38d8fb9709a037009a15b50d56b573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/ejcn.2011.188$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/ejcn.2011.188$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25669709$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22113249$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Järvinen, R</creatorcontrib><creatorcontrib>Tuppurainen, M</creatorcontrib><creatorcontrib>Erkkilä, A T</creatorcontrib><creatorcontrib>Penttinen, P</creatorcontrib><creatorcontrib>Kärkkäinen, M</creatorcontrib><creatorcontrib>Salovaara, K</creatorcontrib><creatorcontrib>Jurvelin, J S</creatorcontrib><creatorcontrib>Kröger, H</creatorcontrib><title>Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women</title><title>European journal of clinical nutrition</title><addtitle>Eur J Clin Nutr</addtitle><addtitle>Eur J Clin Nutr</addtitle><description>Background/Objectives:
Significance of dietary fatty acids on bone health is not clear, and the evidence is controversial. This study aimed to investigate the relationship between dietary polyunsaturated fatty acids (PUFAs) and bone mineral density (BMD) among elderly women.
Subjects/Methods:
Subjects (
n
=554) were drawn from the Kuopio OSTPRE Fracture Prevention Study. At baseline they filled a 3-day food record and a questionnaire on lifestyle factors, diseases and medications. BMD was measured at lumbar spine (L2–L4), femoral neck and total body by dual energy X-ray absorptiometry at baseline and after 3 years. The associations between dietary fatty acids and BMD were analyzed by a linear mixed model adjusting for potential dietary and non-dietary confounders.
Results:
Our findings suggested a positive relationship between the dietary PUFAs and BMD at lumbar spine and in total body but not at femoral neck. Further analyses revealed that these results were due to associations among the women without hormone therapy (HT) at baseline. Among them, the intake of total PUFAs as well the intakes of linoleic and linolenic acids and total n-3 and n-6 fatty acids were significantly associated with BMD at lumbar spine;
P
for trend over the quartiles ranged between 0.013 and 0.001. Similarly, significant associations were demonstrated for total body BMD and fatty acids with an exception of total PUFA. No significant associations were found among women with HT at baseline.
Conclusions:
Our findings among elderly women without HT support the suggested beneficial effect of dietary PUFAs on bone health.</description><subject>Absorptiometry, Photon - methods</subject><subject>Aged</subject><subject>Aged women</subject><subject>alpha-Linolenic Acid - administration & dosage</subject><subject>Biological and medical sciences</subject><subject>Body Mass Index</subject><subject>Bone density</subject><subject>Bone Density - drug effects</subject><subject>Bone mineral density</subject><subject>Bones</subject><subject>Calcium, Dietary - administration & dosage</subject><subject>Clinical Nutrition</subject><subject>Density</subject><subject>Diet</subject><subject>Dietary Fats - administration & dosage</subject><subject>Dual energy X-ray absorptiometry</subject><subject>Epidemiology</subject><subject>Fatty acids</subject><subject>Fatty Acids, Unsaturated - administration & dosage</subject><subject>Feeding. Feeding behavior</subject><subject>Female</subject><subject>Femur</subject><subject>Femur Neck - drug effects</subject><subject>Fish oils</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Linoleic Acid - administration & dosage</subject><subject>Lumbar Vertebrae - drug effects</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolic Diseases</subject><subject>Older people</subject><subject>original-article</subject><subject>Osteoarticular system. Muscles</subject><subject>Osteoporosis</subject><subject>Physiological aspects</subject><subject>Polyunsaturated fatty acids</subject><subject>Prevention</subject><subject>Public Health</subject><subject>Quartiles</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Spine</subject><subject>Spine (lumbar)</subject><subject>Surveys and Questionnaires</subject><subject>Unsaturated fatty acids</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Womens health</subject><issn>0954-3007</issn><issn>1476-5640</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kkuPFCEUhStG47SjS7eGOPGxqRYoqIJlZ-IrmcSNbq1QPLrpUNAClUn_e6mxtdWUhgUJ57v3wuFU1VME1wg27I3eS7_GEKE1YuxetUKka2vaEni_WkFOSd1A2F1Uj1LaQ1jEDj-sLjBGqMGEr6qvm5SCtCLb4BMIBiirs4hHcAjuOPkk8hRF1goYkfMRCGlVArc278AQvAaj9ToKB5T2yRbdeqCd0tEdwW0YtX9cPTDCJf3ktF9WX969_Xz9ob759P7j9eamli0muWYGt5DSjkneQWOQkFoZxgliHA1KGK5lwxQzQ5G5gE0Hy4boQKGi7UC75rJ69aPvIYZvk065H22S2jnhdZhSz1uGIIYQFvL1f0kEeUNIgWlBn_-F7sMUfXlH6ddwwlmDCnT1Lwi3BLcUYdKcqa1wurfehByFnCf3G8wo56Qj893qBWqr7zwudhtbjv_g1wt8WUqPVi4WvPytYKeFy7sU3HT3-4s3kTGkFLXpD9GOJRfFn37OXT_nrp9z15fcFf7ZyYVpGLX6Rf8MWgFenACRpHAmCi9tOnO0bee_PT8pFclvdTzbuTz5O9vf6-s</recordid><startdate>20120401</startdate><enddate>20120401</enddate><creator>Järvinen, R</creator><creator>Tuppurainen, M</creator><creator>Erkkilä, A T</creator><creator>Penttinen, P</creator><creator>Kärkkäinen, M</creator><creator>Salovaara, K</creator><creator>Jurvelin, J S</creator><creator>Kröger, H</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20120401</creationdate><title>Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women</title><author>Järvinen, R ; Tuppurainen, M ; Erkkilä, A T ; Penttinen, P ; Kärkkäinen, M ; Salovaara, K ; Jurvelin, J S ; Kröger, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c624t-8f2605578c970ff1acedf8941891bdaf9ec38d8fb9709a037009a15b50d56b573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Absorptiometry, Photon - methods</topic><topic>Aged</topic><topic>Aged women</topic><topic>alpha-Linolenic Acid - administration & dosage</topic><topic>Biological and medical sciences</topic><topic>Body Mass Index</topic><topic>Bone density</topic><topic>Bone Density - drug effects</topic><topic>Bone mineral density</topic><topic>Bones</topic><topic>Calcium, Dietary - administration & dosage</topic><topic>Clinical Nutrition</topic><topic>Density</topic><topic>Diet</topic><topic>Dietary Fats - administration & dosage</topic><topic>Dual energy X-ray absorptiometry</topic><topic>Epidemiology</topic><topic>Fatty acids</topic><topic>Fatty Acids, Unsaturated - administration & dosage</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Femur</topic><topic>Femur Neck - drug effects</topic><topic>Fish oils</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Linoleic Acid - administration & dosage</topic><topic>Lumbar Vertebrae - drug effects</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metabolic Diseases</topic><topic>Older people</topic><topic>original-article</topic><topic>Osteoarticular system. Muscles</topic><topic>Osteoporosis</topic><topic>Physiological aspects</topic><topic>Polyunsaturated fatty acids</topic><topic>Prevention</topic><topic>Public Health</topic><topic>Quartiles</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Spine</topic><topic>Spine (lumbar)</topic><topic>Surveys and Questionnaires</topic><topic>Unsaturated fatty acids</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Järvinen, R</creatorcontrib><creatorcontrib>Tuppurainen, M</creatorcontrib><creatorcontrib>Erkkilä, A T</creatorcontrib><creatorcontrib>Penttinen, P</creatorcontrib><creatorcontrib>Kärkkäinen, M</creatorcontrib><creatorcontrib>Salovaara, K</creatorcontrib><creatorcontrib>Jurvelin, J S</creatorcontrib><creatorcontrib>Kröger, H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Järvinen, R</au><au>Tuppurainen, M</au><au>Erkkilä, A T</au><au>Penttinen, P</au><au>Kärkkäinen, M</au><au>Salovaara, K</au><au>Jurvelin, J S</au><au>Kröger, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women</atitle><jtitle>European journal of clinical nutrition</jtitle><stitle>Eur J Clin Nutr</stitle><addtitle>Eur J Clin Nutr</addtitle><date>2012-04-01</date><risdate>2012</risdate><volume>66</volume><issue>4</issue><spage>496</spage><epage>503</epage><pages>496-503</pages><issn>0954-3007</issn><eissn>1476-5640</eissn><abstract>Background/Objectives:
Significance of dietary fatty acids on bone health is not clear, and the evidence is controversial. This study aimed to investigate the relationship between dietary polyunsaturated fatty acids (PUFAs) and bone mineral density (BMD) among elderly women.
Subjects/Methods:
Subjects (
n
=554) were drawn from the Kuopio OSTPRE Fracture Prevention Study. At baseline they filled a 3-day food record and a questionnaire on lifestyle factors, diseases and medications. BMD was measured at lumbar spine (L2–L4), femoral neck and total body by dual energy X-ray absorptiometry at baseline and after 3 years. The associations between dietary fatty acids and BMD were analyzed by a linear mixed model adjusting for potential dietary and non-dietary confounders.
Results:
Our findings suggested a positive relationship between the dietary PUFAs and BMD at lumbar spine and in total body but not at femoral neck. Further analyses revealed that these results were due to associations among the women without hormone therapy (HT) at baseline. Among them, the intake of total PUFAs as well the intakes of linoleic and linolenic acids and total n-3 and n-6 fatty acids were significantly associated with BMD at lumbar spine;
P
for trend over the quartiles ranged between 0.013 and 0.001. Similarly, significant associations were demonstrated for total body BMD and fatty acids with an exception of total PUFA. No significant associations were found among women with HT at baseline.
Conclusions:
Our findings among elderly women without HT support the suggested beneficial effect of dietary PUFAs on bone health.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>22113249</pmid><doi>10.1038/ejcn.2011.188</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0954-3007 |
| ispartof | European journal of clinical nutrition, 2012-04, Vol.66 (4), p.496-503 |
| issn | 0954-3007 1476-5640 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_968102000 |
| source | MEDLINE; SpringerLink Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Absorptiometry, Photon - methods Aged Aged women alpha-Linolenic Acid - administration & dosage Biological and medical sciences Body Mass Index Bone density Bone Density - drug effects Bone mineral density Bones Calcium, Dietary - administration & dosage Clinical Nutrition Density Diet Dietary Fats - administration & dosage Dual energy X-ray absorptiometry Epidemiology Fatty acids Fatty Acids, Unsaturated - administration & dosage Feeding. Feeding behavior Female Femur Femur Neck - drug effects Fish oils Fundamental and applied biological sciences. Psychology Health aspects Humans Internal Medicine Investigative techniques, diagnostic techniques (general aspects) Linoleic Acid - administration & dosage Lumbar Vertebrae - drug effects Medical sciences Medicine Medicine & Public Health Metabolic Diseases Older people original-article Osteoarticular system. Muscles Osteoporosis Physiological aspects Polyunsaturated fatty acids Prevention Public Health Quartiles Radiodiagnosis. Nmr imagery. Nmr spectrometry Spine Spine (lumbar) Surveys and Questionnaires Unsaturated fatty acids Vertebrates: anatomy and physiology, studies on body, several organs or systems Womens health |
| title | Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women |
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