Localization of an absorber in a turbid semi-infinite medium by spatially resolved continuous-wave diffuse reflectance measurements

A method to locate an absorber embedded in a semi-infinite turbid medium by spatially-resolved continuous-wave (SRCW) diffuse reflectance measurements is introduced. The depth of the absorber is assessed by single wavelength SRCW diffuse reflectance measurements by two detectors in a radial row. The...

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Veröffentlicht in:Journal of Biomedical Optics 2011-08, Vol.16 (8), p.086010-086010
Hauptverfasser: Aksel, Ertugrul B, Turkoglu, Ahu N, Akin, Ata, Ercan, Ayse Ece
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container_issue 8
container_start_page 086010
container_title Journal of Biomedical Optics
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creator Aksel, Ertugrul B
Turkoglu, Ahu N
Akin, Ata
Ercan, Ayse Ece
description A method to locate an absorber embedded in a semi-infinite turbid medium by spatially-resolved continuous-wave (SRCW) diffuse reflectance measurements is introduced. The depth of the absorber is assessed by single wavelength SRCW diffuse reflectance measurements by two detectors in a radial row. The ratio of perturbations introduced by the defect at two detectors is used to be matched with the ratio-versus-depth curve, which are generated by approximate formulas of continuous wave diffuse reflectance. The error due to approximation and the error in depth assessment are studied for different cases revealing favorable source-detector placements with respect to planar position of the defect. The effect of lateral displacement of the source with respect to defect is studied. A strategy to overcome errors introduced by erroneous prediction of background medium optical properties is suggested. Theoretical results indicate that the depth of the absorber can be obtained with 0.1 mm precision independent of its absorption coefficient and its size for the values chosen in the study. The approach is tested experimentally and it is observed that theoretical results fit with experimental data.
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source MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Absorption
Approximation
Assessments
Computer Simulation
Defects
Detectors
Diffusion
Emulsions - chemistry
Error analysis
Infrared Rays
Light
Models, Chemical
Nephelometry and Turbidimetry - methods
Phospholipids - chemistry
Reflectance
Reflectivity
Scattering, Radiation
Signal Processing, Computer-Assisted
Soybean Oil - chemistry
title Localization of an absorber in a turbid semi-infinite medium by spatially resolved continuous-wave diffuse reflectance measurements
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