Corrosion of magnesium alloy AZ31 screws is dependent on the implantation site

The corrosion of biodegradable materials is a crucial issue in implant development. Among other materials, magnesium and magnesium based alloys are one of the most promising candidates. Since the corrosion of biodegradable materials depends on different physiological parameters like pH or ion concen...

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Veröffentlicht in:Materials science & engineering. B, Solid-state materials for advanced technology Solid-state materials for advanced technology, 2011-12, Vol.176 (20), p.1835-1840
Hauptverfasser: Willbold, E., Kaya, A.A., Kaya, R.A., Beckmann, F., Witte, F.
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container_end_page 1840
container_issue 20
container_start_page 1835
container_title Materials science & engineering. B, Solid-state materials for advanced technology
container_volume 176
creator Willbold, E.
Kaya, A.A.
Kaya, R.A.
Beckmann, F.
Witte, F.
description The corrosion of biodegradable materials is a crucial issue in implant development. Among other materials, magnesium and magnesium based alloys are one of the most promising candidates. Since the corrosion of biodegradable materials depends on different physiological parameters like pH or ion concentrations, the corrosion might be different in different biological environments. To investigate this issue, we produced screws from magnesium alloy AZ31 and implanted them into the hip bone of 14 sheep. After 3 and 6 months, the screws were explanted and analyzed with synchrotron-radiation based micro-computed tomography and hard tissue histology. We found considerable differences in the corrosion behavior of the magnesium screws with respect to its original tissue location. However, we could detect a normal immunological tissue response.
doi_str_mv 10.1016/j.mseb.2011.02.010
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source ScienceDirect Journals (5 years ago - present)
subjects Biodegradability
Biodegradable
Bones
Corrosion
Corrosion environments
Histology
Implantation
Implants
Magnesium
Magnesium base alloys
Screws
Synchrotron-radiation based micro-computed tomography
title Corrosion of magnesium alloy AZ31 screws is dependent on the implantation site
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