Corrosion of magnesium alloy AZ31 screws is dependent on the implantation site
The corrosion of biodegradable materials is a crucial issue in implant development. Among other materials, magnesium and magnesium based alloys are one of the most promising candidates. Since the corrosion of biodegradable materials depends on different physiological parameters like pH or ion concen...
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Veröffentlicht in: | Materials science & engineering. B, Solid-state materials for advanced technology Solid-state materials for advanced technology, 2011-12, Vol.176 (20), p.1835-1840 |
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creator | Willbold, E. Kaya, A.A. Kaya, R.A. Beckmann, F. Witte, F. |
description | The corrosion of biodegradable materials is a crucial issue in implant development. Among other materials, magnesium and magnesium based alloys are one of the most promising candidates. Since the corrosion of biodegradable materials depends on different physiological parameters like pH or ion concentrations, the corrosion might be different in different biological environments. To investigate this issue, we produced screws from magnesium alloy AZ31 and implanted them into the hip bone of 14 sheep. After 3 and 6 months, the screws were explanted and analyzed with synchrotron-radiation based micro-computed tomography and hard tissue histology. We found considerable differences in the corrosion behavior of the magnesium screws with respect to its original tissue location. However, we could detect a normal immunological tissue response. |
doi_str_mv | 10.1016/j.mseb.2011.02.010 |
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Among other materials, magnesium and magnesium based alloys are one of the most promising candidates. Since the corrosion of biodegradable materials depends on different physiological parameters like pH or ion concentrations, the corrosion might be different in different biological environments. To investigate this issue, we produced screws from magnesium alloy AZ31 and implanted them into the hip bone of 14 sheep. After 3 and 6 months, the screws were explanted and analyzed with synchrotron-radiation based micro-computed tomography and hard tissue histology. We found considerable differences in the corrosion behavior of the magnesium screws with respect to its original tissue location. 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However, we could detect a normal immunological tissue response.</description><subject>Biodegradability</subject><subject>Biodegradable</subject><subject>Bones</subject><subject>Corrosion</subject><subject>Corrosion environments</subject><subject>Histology</subject><subject>Implantation</subject><subject>Implants</subject><subject>Magnesium</subject><subject>Magnesium base alloys</subject><subject>Screws</subject><subject>Synchrotron-radiation based micro-computed tomography</subject><issn>0921-5107</issn><issn>1873-4944</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNp9kDtPwzAQgC0EEqXwB5i8wZJw58R5SCxVxUuqYIGFxXLtC7jKo9guqP-eRGVmuuX7TncfY5cIKQIWN5u0C7ROBSCmIFJAOGIzrMosyes8P2YzqAUmEqE8ZWchbAAAhRAz9rwcvB-CG3o-NLzTHz0Ft-u4btthzxfvGfJgPP0E7gK3tKXeUh_5iMdP4q7btrqPOk5-cJHO2Umj20AXf3PO3u7vXpePyerl4Wm5WCUmzzAmppA2z60sGg2lbiQK1LWuq3ItSqubTBOgBiHB1jq3GcgKjEVprSiFMWvI5uzqsHfrh68dhag6Fwy14zU07IKqi6ySWSFwJK__JbGsCixkUYoRFQfUjEWCp0Ztveu03ysENWVWGzVlVlNmBUKNmUfp9iDR-O63I6-CcdQbss6TicoO7j_9F91uhaQ</recordid><startdate>20111215</startdate><enddate>20111215</enddate><creator>Willbold, E.</creator><creator>Kaya, A.A.</creator><creator>Kaya, R.A.</creator><creator>Beckmann, F.</creator><creator>Witte, F.</creator><general>Elsevier B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7SE</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20111215</creationdate><title>Corrosion of magnesium alloy AZ31 screws is dependent on the implantation site</title><author>Willbold, E. ; Kaya, A.A. ; Kaya, R.A. ; Beckmann, F. ; Witte, F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-c65d44d56fa07af5121a9a987b27daf3ae01a0250d9a4d30580cd15dd272ccb03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Biodegradability</topic><topic>Biodegradable</topic><topic>Bones</topic><topic>Corrosion</topic><topic>Corrosion environments</topic><topic>Histology</topic><topic>Implantation</topic><topic>Implants</topic><topic>Magnesium</topic><topic>Magnesium base alloys</topic><topic>Screws</topic><topic>Synchrotron-radiation based micro-computed tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Willbold, E.</creatorcontrib><creatorcontrib>Kaya, A.A.</creatorcontrib><creatorcontrib>Kaya, R.A.</creatorcontrib><creatorcontrib>Beckmann, F.</creatorcontrib><creatorcontrib>Witte, F.</creatorcontrib><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Materials science & engineering. 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source | ScienceDirect Journals (5 years ago - present) |
subjects | Biodegradability Biodegradable Bones Corrosion Corrosion environments Histology Implantation Implants Magnesium Magnesium base alloys Screws Synchrotron-radiation based micro-computed tomography |
title | Corrosion of magnesium alloy AZ31 screws is dependent on the implantation site |
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