Thermal characterization of antimicrobial drug ornidazole and its compatibility in a solid pharmaceutical product

The ornidazole drug substance presents melt at approximately 90 °C (∆T = 85–98 °C), which is critical for its use on pharmaceutical manufacturing process. This work aimed the thermal characterization of ornidazole raw-material synthesized by three different manufacturers from India, China, and Ital...

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Veröffentlicht in:	Journal of thermal analysis and calorimetry 2011-04, Vol.104 (1), p.307-313
Hauptverfasser:	Soares, Monica Felts de La Roca, Soares-Sobrinho, José Lamartine, da Silva, Keyla Emanuelle Ramos, Alves, Lariza Darlene Santos, Lopes, Pablo Queiroz, Correia, Lidiane Pinto, de Souza, Fábio Santos, Macêdo, Rui Oliveira, Rolim-Neto, Pedro José
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical Chemistry Biological and medical sciences Chemistry Chemistry and Materials Science Drugs Excipients General pharmacology Inorganic Chemistry Liquid chromatography Mathematical analysis Mathematical models Measurement Science and Instrumentation Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmaceuticals Pharmacology. Drug treatments Physical Chemistry Polymer Sciences Production processes Purity Raw materials Tablets Thermal analysis
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