Site specific chemoselective labelling of proteins with robust and highly sensitive Ru(II) bathophenanthroline complexes

The bioorthogonal and chemoselective fluorescence labelling of several cell-free synthesized proteins containing a site-specifically incorporated azido amino acid was possible using different alkyne-functionalized Ru(II) bathophenanthroline complexes. We were able to achieve a selective labelling ev...

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Veröffentlicht in:	Organic & biomolecular chemistry 2012-03, Vol.10 (11), p.2223-2226
Hauptverfasser:	Uzagare, Matthew C, Claussnitzer, Iris, Gerrits, Michael, Bannwarth, Willi
Format:	Artikel
Sprache:	eng
Schlagworte:	Molecular Structure Phenanthrolines - chemistry Proteins - analysis Proteins - chemistry Ruthenium - chemistry
Online-Zugang:	Volltext
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